Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | CKS1B | P61024 | 4/20 | 0.40 |
| ▸ | SKP1 | P63208 | 4/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 4/20 | 0.40 |
| ▸ | UBE2M | P61081 | 1/20 | 0.39 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.39 |
| ▸ | CCKAR | P32238 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5777253 | 0.81 | HRH3 (0.52) | HTR3ASLC6A4 | |
| SCHEMBL1710989 | 0.79 | CNR1 (0.47) | UBE2MDCUN1D1SLC6A4KCNH2SLC6A2 | |
| SCHEMBL1728431 | 0.78 | HTR3E (0.47) | HTR3AOPRM1KCNH2 | |
| SCHEMBL5780030 | 0.77 | CYP11B2 (0.48) | OPRM1 | |
| SCHEMBL5709408 | 0.74 | ACHE (0.59) | OPRM1 | |
| SCHEMBL1722964 | 0.74 | PDE10A (0.44) | OPRM1 | |
| SCHEMBL27649153 | 0.74 | CKS1B (0.52) | HTR3ACKS1BSKP1SKP2 | |
| SCHEMBL5779772 | 0.74 | HRH3 (0.43) | OPRM1UBE2MDCUN1D1USP30 | |
| SCHEMBL1729264 | 0.73 | HTR3A (0.41) | HTR3ACXCR3CKS1BSKP1SKP2 | |
| SCHEMBL1730251 | 0.73 | DPP4 (0.42) | HTR3ACXCR3CKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1812980-B | Piperidinyl-and piperazinyl-alkylcarbamate derivatives, their preparation and their use as pharmaceuticals | SANOFI AVENTIS | 2011-04-06 | — | — | CN | disclosed |
| CN-101712660-A | Piperidinyl-and piperazinyl-alkylcarbamate derivatives, their preparation and their therapeutic use | SANOFI AVENTIS | 2010-05-26 | — | — | CN | disclosed |
| CN-1812980-A | Piperidinyl-and piperazinyl-alkylcarbamate derivatives, their preparation and their therapeutic use | SANOFI AVENTIS (FR) | 2006-08-02 | — | — | CN | disclosed |
| EP-1633735-A1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | Sanofi-Aventis (FR) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004099176-A1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2004-11-18 | — | — | WO | disclosed |