Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5776546 | 0.86 | CYP4A11 (0.57) | LOXL2SMN1; SMN2KDM4EALDH1A1MAPK1 | |
| SCHEMBL3036189 | 0.83 | PRMT1 (0.52) | LOXL2SMN1; SMN2KDM4EALDH1A1MAPK1 | |
| SCHEMBL23423391 | 0.82 | LOXL2 (0.56) | LOXL2SMN1; SMN2KDM4EALDH1A1MAPK1 | |
| SCHEMBL13052122 | 0.81 | ACHE (0.66) | LOXL2SMN1; SMN2KDM4EALDH1A1NPC1 | |
| SCHEMBL9826363 | 0.81 | SMN1; SMN2 (0.58) | SMN1; SMN2KDM4EALDH1A1TSHRCYP4A11 | |
| SCHEMBL846524 | 0.81 | SIGMAR1 (0.51) | LOXL2SMN1; SMN2KDM4EALDH1A1MAPK1 | |
| SCHEMBL5067508 | 0.80 | LOXL2 (0.61) | LOXL2SMN1; SMN2KDM4EALDH1A1MAPK1 | |
| SCHEMBL5656954 | 0.80 | LTA4H (0.51) | LOXL2SMN1; SMN2KDM4EALDH1A1MAPK1 | |
| SCHEMBL1638297 | 0.79 | SIGMAR1 (0.47) | LOXL2SMN1; SMN2KDM4EALDH1A1MAPK1 | |
| SCHEMBL8781971 | 0.78 | LOXL2 (0.59) | LOXL2SMN1; SMN2KDM4EALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1612204-A1 | HYDRAZONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | APP, PRNP, HTT | LOXL2 3994/4885SMN1; SMN2 2146/4885KDM4E 4325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.