Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 3/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5776131 | 0.95 | LMNA (0.42) | MCHR1LMNAL3MBTL1CYP3A4MEN1 | |
| Trifluoroacetic Acid SCHEMBL5774584 | 0.87 | MEN1 (0.44) | MCHR1MEN1KMT2ACCR5CHRM3 | |
| Trifluoroacetic Acid SCHEMBL5773114 | 0.87 | LMNA (0.41) | MCHR1LMNAL3MBTL1CYP3A4KMT2A | |
| Trifluoroacetic Acid SCHEMBL5772282 | 0.83 | LMNA (0.39) | MCHR1LMNAL3MBTL1CYP3A4KMT2A | |
| Trifluoroacetic Acid SCHEMBL5773443 | 0.81 | LMNA (0.41) | MCHR1LMNAL3MBTL1CYP3A4MEN1 | |
| SCHEMBL5772900 | 0.80 | BACE1 (0.46) | LMNAL3MBTL1MEN1KMT2AGRIN2B | |
| Trifluoroacetic Acid SCHEMBL5776834 | 0.78 | HTT (0.46) | LMNAKMT2ADPP7DPP8HDAC8 | |
| Trifluoroacetic Acid SCHEMBL5770496 | 0.77 | HDAC4 (0.36) | MCHR1GRIN2BDPP4DPP7DPP8 | |
| Trifluoroacetic Acid SCHEMBL5773674 | 0.77 | OPRM1 (0.47) | LMNACHRM3 | |
| Trifluoroacetic Acid SCHEMBL5776847 | 0.73 | MDM2 (0.39) | L3MBTL1MEN1KMT2ADPP7DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060084690-A1 | Isoxazole derivatives | MOMOSE YU | 2006-04-20 | — | — | US | disclosed |
| US-7022725-B2 | Isoxazole derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-04-04 | — | — | US | disclosed |
| US-20040048908-A1 | Isoxazole derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-03-11 | — | — | US | disclosed |
| EP-1340749-A1 | ISOXAZOLE DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2003-09-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060084690-A1 | Isoxazole derivatives | INSR, GPR119, INSRR | MCHR1 2026/4885LMNA 2770/4885L3MBTL1 2718/4885 |
| US-20040048908-A1 | Isoxazole derivatives | GPR119, INSR, IRS1 | MCHR1 2036/4885LMNA 2605/4885L3MBTL1 1898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.