Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SPR | P35270 | 1/20 | 0.45 |
| ▸ | NPEPPS | P55786 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5871674 | 0.79 | SMN1; SMN2 (0.50) | CSF1RRECQLSPRMEN1KMT2A | |
| SCHEMBL5872120 | 0.73 | LMNA (0.48) | CSF1RMEN1KMT2AALDH1A1GAA | |
| SCHEMBL22172011 | 0.69 | KDM4C (0.47) | ALDH1A1ATMKDM4EHTT | |
| SCHEMBL22845404 | 0.69 | ALDH1A1 (0.47) | RECQLMEN1KMT2AALDH1A1GAA | |
| SCHEMBL25942232 | 0.68 | ALDH1A1 (0.51) | SPRKMT2AKDM5AKDM5BALDH1A1 | |
| SCHEMBL18044696 | 0.68 | ALDH1A1 (0.50) | CSF1RRECQLMEN1KMT2AALDH1A1 | |
| SCHEMBL11789226 | 0.68 | MAPT (0.60) | RECQLMEN1KMT2AALDH1A1GAA | |
| SCHEMBL5777622 | 0.67 | CDK4 (0.41) | ALDH1A1GAA | |
| SCHEMBL22172017 | 0.66 | KDM4E (0.53) | KMT2AATMKDM4EHTT | |
| SCHEMBL8287988 | 0.66 | CSF1R (0.47) | CSF1RSPRPDE4BALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513840-B1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF DIABETES AND DIABETES-RELATED DISORDERS | BAYER PHARMACEUTICALS CORP (US) | 2006-10-04 | — | — | EP | disclosed |
| US-20060009483-A1 | Compounds and compositions for the treatment of diabetes and diabetes-related disorders | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-01-12 | — | — | US | disclosed |
| EP-1513840-A2 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF DIABETES AND DIABETES-RELATED DISORDERS | Bayer Pharmaceuticals Corporation (US) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003101988-A2 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF DIABETES AND DIABETES-RELATED DISORDERS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060009483-A1 | Compounds and compositions for the treatment of diabetes and diabetes-related disorders | IAPP, GPR119, PNLIP | CSF1R 4716/4885RECQL 792/4885SPR 2490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.