Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | TACR1 | P25103 | 9/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | TACR3 | P29371 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5770010 | 0.92 | HTR1A (0.49) | L3MBTL1TACR1MAPTMEN1LMNA | |
| Trifluoroacetic Acid SCHEMBL5775195 | 0.90 | ATM (0.49) | L3MBTL1MAPTKMT2ATP53 | |
| Trifluoroacetic Acid SCHEMBL5775321 | 0.90 | KMT2A (0.53) | L3MBTL1MAPTMEN1LMNAKMT2A | |
| Trifluoroacetic Acid SCHEMBL5776836 | 0.89 | PARP1 (0.44) | L3MBTL1MAPTMEN1KMT2ATP53 | |
| Trifluoroacetic Acid SCHEMBL5772610 | 0.87 | GFER (0.53) | MAPTMEN1LMNAKMT2APOLB | |
| Trifluoroacetic Acid SCHEMBL5771192 | 0.86 | MEN1 (0.53) | L3MBTL1MAPTTHRBMEN1LMNA | |
| Trifluoroacetic Acid SCHEMBL5775548 | 0.85 | MAPT (0.53) | L3MBTL1MAPTMEN1LMNAKMT2A | |
| Trifluoroacetic Acid SCHEMBL5777433 | 0.85 | GFER (0.53) | MAPTMEN1LMNAKMT2ATP53 | |
| Trifluoroacetic Acid SCHEMBL5776834 | 0.84 | HTT (0.46) | MAPTLMNAKMT2APOLBHTR7 | |
| Trifluoroacetic Acid SCHEMBL5776691 | 0.84 | GRM5 (0.48) | L3MBTL1MAPTPOLBHTR7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060084690-A1 | Isoxazole derivatives | MOMOSE YU | 2006-04-20 | — | — | US | disclosed |
| US-7022725-B2 | Isoxazole derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-04-04 | — | — | US | disclosed |
| US-20040048908-A1 | Isoxazole derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-03-11 | — | — | US | disclosed |
| EP-1340749-A1 | ISOXAZOLE DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2003-09-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060084690-A1 | Isoxazole derivatives | INSR, GPR119, INSRR | L3MBTL1 2718/4885TACR1 3603/4885MAPT 4701/4885 |
| US-20040048908-A1 | Isoxazole derivatives | GPR119, INSR, IRS1 | L3MBTL1 1898/4885TACR1 4234/4885MAPT 4763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.