Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CCR4 | P51679 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | OGA | O60502 | 1/20 | 0.30 |
| ▸ | ALB | P02768 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8276154 | 0.81 | MEN1 (0.39) | KMT2AMEN1POLBRAB9AALDH1A1 | |
| SCHEMBL2644083 | 0.79 | MEN1 (0.38) | KMT2AMEN1POLBRAB9AALDH1A1 | |
| SCHEMBL2628923 | 0.79 | KMT2A (0.44) | KMT2AMEN1POLBRAB9AALDH1A1 | |
| SCHEMBL13986776 | 0.79 | MEN1 (0.38) | KMT2AMEN1POLBRAB9AALDH1A1 | |
| SCHEMBL9258490 | 0.79 | KMT2A (0.38) | KMT2AMEN1POLBRAB9AALDH1A1 | |
| SCHEMBL2644081 | 0.79 | KMT2A (0.38) | KMT2AMEN1POLBRAB9AALDH1A1 | |
| SCHEMBL5779345 | 0.79 | KMT2A (0.38) | KMT2AMEN1POLBRAB9AALDH1A1 | |
| SCHEMBL12120609 | 0.79 | ALDH1A1 (0.40) | KMT2AMEN1POLBRAB9AALDH1A1 | |
| SCHEMBL12844161 | 0.78 | SLC6A3 (0.40) | KMT2AMEN1POLBRAB9AALDH1A1 | |
| SCHEMBL12776037 | 0.76 | KMT2A (0.36) | KMT2AMEN1POLBRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11129814-B2 | Antimicrobial agents | TAXIS PHARMACEUTICALS, INC. (US) | 2021-09-28 | — | — | US | disclosed |
| US-11129814-B2 | Antimicrobial agents | TAXIS PHARMACEUTICALS, INC. (US) | 2021-09-28 | — | — | US | disclosed |
| US-20180338957-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-11-29 | — | — | US | disclosed |
| US-10071082-B2 | Antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-09-11 | — | — | US | disclosed |
| US-20160367531-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-12-22 | — | — | US | disclosed |
| US-20160367531-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-12-22 | — | — | US | disclosed |
| US-20160367531-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-12-22 | — | — | US | disclosed |
| US-9458150-B2 | Antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-10-04 | — | — | US | disclosed |
| US-9458150-B2 | Antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-10-04 | — | — | US | disclosed |
| US-9458150-B2 | Antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-10-04 | — | — | US | disclosed |
| EP-1227084-B1 | DRUG DISCHARGE PUMP INHIBITORS | TRINE PHARMACEUTICALS INC (US) | 2005-12-14 | — | — | EP | disclosed |
| US-20050009843-A1 | Medicine for inhibiting drug elimination pump | TRINE PHARMACEUTICALS, INC. | 2005-01-13 | — | — | US | disclosed |
| EP-1389463-A1 | MEDICINE FOR INHIBITING DRUG ELIMINATION PUMP | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
| US-20030092720-A1 | Drug efflux pump inhibitor | DAIICHI PHARMACEUTICAL CO., LTD (JP) | 2003-05-15 | — | — | US | disclosed |
| CN-1414951-A | Drug discharge pump inhibitor | FUNDAMENTAL THERAPEUTICAL INC (US) | 2003-04-30 | — | — | CN | disclosed |
| EP-1227084-A1 | DRUG DISCHARGE PUMP INHIBITORS | Microcide Pharmaceuticals, Inc. (US) | 2002-07-31 | — | — | EP | disclosed |
| US-5455351-A | Treating HIV or AIDS | ABBOTT LABORATORIES (US) | 1995-10-03 | — | — | US | disclosed |
| US-5290798-A | Antihistamines, antiallergens, antiinflammatory agents | MERCK FROSST CANADA, INC. (CA) | 1994-03-01 | — | — | US | disclosed |
| WO-1993021168-A1 | THIAZOLE-SUBSTITUTED BENZYL ALCOHOLS AS LEUKOTRIENE ANTAGONISTS | MERCK FROSST CANADA INC. (CA) | 1993-10-28 | — | — | WO | disclosed |
| EP-0535926-A1 | (Hetero-arylmethoxy) indoles as inhibitors of leukotriene biosynthesis | MERCK FROSST CANADA INC. (CA) | 1993-04-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180338957-A1 | ANTIMICROBIAL AGENTS | MRPL21, SPOUT1, LSS | KMT2A 4343/4885MEN1 3062/4885POLB 186/4885 |
| US-11129814-B2 | Antimicrobial agents | MRPL21, SPOUT1, LSS | KMT2A 4343/4885MEN1 3062/4885POLB 186/4885 |
| US-20160367531-A1 | ANTIMICROBIAL AGENTS | CFTR, MRPL21, ARG1 | KMT2A 4507/4885MEN1 1168/4885POLB 2530/4885 |
| US-10071082-B2 | Antimicrobial agents | CFTR, MRPL21, ARG1 | KMT2A 4507/4885MEN1 1168/4885POLB 2530/4885 |
| US-20030092720-A1 | Drug efflux pump inhibitor | ABCB11, ABCB1, ABCC1 | KMT2A 3288/4885MEN1 4800/4885POLB 3005/4885 |
| US-20050009843-A1 | Medicine for inhibiting drug elimination pump | ABCB11, ATP6AP1, HRH2 | KMT2A 3458/4885MEN1 3567/4885POLB 3610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.