Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.61 |
| ▸ | TYK2 | P29597 | 1/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.46 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL393417 | 0.85 | ALDH1A1 (0.48) | EPHX1SMN1; SMN2KCNK3ALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL9773792 | 0.83 | ALDH1A1 (0.46) | EPHX1SMN1; SMN2KCNK3ALDH1A1CYP3A4 | |
| SCHEMBL457388 | 0.83 | ALDH1A1 (0.46) | EPHX1SMN1; SMN2KCNK3ALDH1A1CYP3A4 | |
| SCHEMBL23410460 | 0.81 | KMT2A (0.64) | JAK2TYK2SMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL5782175 | 0.81 | RAB9A (0.50) | POLBSMN1; SMN2ROCK2ROCK1KDM4E | |
| SCHEMBL455628 | 0.79 | NAMPT (0.56) | SMN1; SMN2ROCK2ROCK1L3MBTL1KCNK3 | |
| SCHEMBL5783437 | 0.79 | NAMPT (0.65) | HTTSMN1; SMN2KDM4EL3MBTL1KCNK3 | |
| SCHEMBL14223760 | 0.78 | GAA (0.50) | HTTSMN1; SMN2BCHEKDM4EL3MBTL1 | |
| SCHEMBL19937963 | 0.78 | GAA (0.53) | HTTPOLBKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL4861779 | 0.77 | CA1 (0.53) | POLBSMN1; SMN2KDM4EL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060189591-A1 | Five-membered heterocyclic derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-08-24 | — | — | US | disclosed |
| EP-1621537-A1 | FIVE-MEMBERED HETEROCYCLIC DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-02-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189591-A1 | Five-membered heterocyclic derivative | PTGS1, PTGIS, PTGS2 | JAK2 68/4885TYK2 3827/4885TAAR1 4603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.