Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | DAGLA | Q9Y4D2 | 11/20 | 0.48 |
| ▸ | ABHD6 | Q9BV23 | 4/20 | 0.48 |
| ▸ | DAGLB | Q8NCG7 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3542189 | 0.76 | GAA (0.56) | LMNAGAATSHRNPSR1ALDH1A1 | |
| SCHEMBL4629395 | 0.74 | HSD11B1 (0.61) | DAGLAABHD6DAGLB | |
| SCHEMBL4964339 | 0.74 | HSD11B1 (0.61) | DAGLAABHD6DAGLB | |
| Hydrochloric Acid SCHEMBL29238125 | 0.73 | HSD11B1 (0.60) | DAGLAABHD6DAGLB | |
| SCHEMBL23459127 | 0.70 | SCD5 (0.57) | DAGLAABHD6 | |
| SCHEMBL7709183 | 0.70 | LMNA (0.63) | LMNATSHRHPGDSMN1; SMN2 | |
| SCHEMBL908981 | 0.70 | SCD5 (0.57) | DAGLAABHD6 | |
| SCHEMBL30360947 | 0.69 | HRH3 (0.54) | GAADAGLAABHD6DAGLBALDH1A1 | |
| SCHEMBL5181319 | 0.68 | PARP14 (0.44) | GAADAGLAABHD6DAGLB | |
| SCHEMBL27630774 | 0.67 | NPC1 (0.64) | DAGLAABHD6DAGLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572668-A4 | N-(SUBSTITUTED ARYLMETHYL)-4-(DISUBSTITUTED METHYL)PIPERIDINES AND PIPERAZINES | FMC CORP (US) | 2006-12-06 | — | — | EP | disclosed |
| EP-1572207-A4 | N-(SUBSTITUTED ARYLMETHYL)-4-(DISUBSTITUTED METHYL) PIPERIDINES AND PYRIDINES | FMC CORP (US) | 2006-11-29 | — | — | EP | disclosed |
| EP-1572207-A1 | N-(SUBSTITUTED ARYLMETHYL)-4-(DISUBSTITUTED METHYL) PIPERIDINES AND PYRIDINES | FMC CORPORATION (US) | 2005-09-14 | — | — | EP | disclosed |
| EP-1572668-A2 | N-(SUBSTITUTED ARYLMETHYL)-4-(DISUBSTITUTED METHYL)PIPERIDINES AND PIPERAZINES | FMC CORPORATION (US) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004060865-A2 | N-(SUBSTITUTED ARYLMETHYL)-4-(DISUBSTITUTED METHYL)PIPERIDINES AND PIPERAZINES | FMC CORPORATION (US) | 2004-07-22 | — | — | WO | disclosed |
| WO-2004060371-A1 | N-(SUBSTITUTED ARYLMETHYL)-4-(DISUBSTITUTED METHYL) PIPERIDINES AND PYRIDINES | FMC CORPORATION (US) | 2004-07-22 | — | — | WO | disclosed |