Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 6/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6051263 | 0.85 | HTR6 (0.43) | HTR6HSD11B1TP53 | |
| SCHEMBL5786541 | 0.84 | HTR6 (0.42) | HTR6HSD11B1TP53 | |
| SCHEMBL5786579 | 0.84 | MEN1 (0.40) | HTR6LMNA | |
| SCHEMBL5781386 | 0.84 | HTR6 (0.38) | HTR6LMNATP53 | |
| SCHEMBL5697885 | 0.83 | LMNA (0.39) | HTR6LMNA | |
| SCHEMBL5781878 | 0.82 | TSHR (0.44) | LMNA | |
| SCHEMBL5697915 | 0.81 | HTR6 (0.37) | HTR6LMNA | |
| SCHEMBL5815922 | 0.80 | PKM (0.38) | HTR6LMNA | |
| SCHEMBL5784055 | 0.80 | GBA1 (0.40) | HTR6 | |
| SCHEMBL5785250 | 0.79 | HTR6 (0.38) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648886-A1 | BENZOXAZINONE-DERIVED SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2006-04-26 | — | — | EP | claimed |
| WO-2005014589-A1 | BENZOXAZINONE-DERIVED SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE S.A. (DE) | 2005-02-17 | — | — | WO | claimed |