Sugi Predict

Sugi Predict / Compounds / SCHEMBL578535

SCHEMBL578535

SCHEMBL578535

CC1(C)OB(c2ccc(OCCO)cc2)OC1(C)C

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ LPL P06858 12/20 0.50
▸ LIPG Q9Y5X9 12/20 0.50
▸ CA1 P00915 1/20 0.50
▸ CA2 P00918 1/20 0.50
▸ CA9 Q16790 1/20 0.50
▸ DGAT1 O75907 1/20 0.47
▸ F11 P03951 1/20 0.45
▸ NR1I2 O75469 1/20 0.45
▸ AAK1 Q2M2I8 1/20 0.44
▸ ALDH1A1 P00352 1/20 0.44
▸ RECQL P46063 1/20 0.44
▸ HIF1A Q16665 1/20 0.43
▸ ESR2 Q92731 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2020518 0.92 CA1 (0.49) LPLLIPGCA1CA2CA9
SCHEMBL15786149 0.91 APP (0.46) LPLLIPGCA1CA2CA9
SCHEMBL24573014 0.91 APP (0.46) LPLLIPGCA1CA2CA9
SCHEMBL14211671 0.91 APP (0.46) LPLLIPGCA1CA2CA9
SCHEMBL18428794 0.91 APP (0.46) LPLLIPGCA1CA2CA9
SCHEMBL427591 0.90 CA1 (0.56) LPLLIPGCA1CA2CA9
SCHEMBL22748350 0.89 LPL (0.47) LPLLIPGCA1CA2CA9
SCHEMBL15579042 0.87 CA1 (0.50) LPLLIPGCA1CA2CA9
SCHEMBL428836 0.86 LPL (0.53) LPLLIPGCA1CA2CA9
SCHEMBL25405585 0.86 LPL (0.53) LPLLIPGCA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5563151-A PLATELET ACTIVATING FACTOR RECEPTOR ANTAGONISTS; ANTIINFLAMMATORY AGENTS, ANALGESICS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1996-10-08 — — US claimed
US-20260115296-A1 COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF RAPIDLY ACCELERATED FIBROSARCOMA POLYPEPTIDES UNIV YALE (US) 2026-04-30 — — US disclosed
EP-4344702-B1 PYRAZOLYL DERIVATIVES USEFUL AS ANTI-CANCER AGENTS NOVARTIS AG (CH) 2026-01-28 — — EP disclosed
CN-118852176-A Spiro compound, and pharmaceutical composition and application thereof 中国药科大学 2024-10-29 — — CN disclosed
WO-2024140638-A1 COMPOUND BASED ON SULFUR/OXYGEN SUBSTITUTED GLUTARIMIDE-BASED ISOINDOLINONE SKELETON AND USE THEREOF 标新生物医药科技(上海)有限公司 2024-07-04 — — WO disclosed
CN-118271627-A Multipolymer, preparation method thereof, polymer electrolyte and lithium ion battery 比亚迪股份有限公司 2024-07-02 — — CN disclosed
CN-118201905-A Cationic lipid 武田药品工业株式会社 2024-06-14 — — CN disclosed
US-20240191093-A1 INKJET INK, INKJET RECORDING METHOD, INK SET, INK MEDIUM SET, AND PRINT MEDIUM NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2024-06-13 — — US disclosed
EP-4373886-A1 AN ADDITIVE MIXTURE FOR STABILIZATION OF ORGANIC MATERIAL BASF SE (DE) 2024-05-29 — — EP disclosed
US-11986531-B2 Compounds and methods for the targeted degradation of rapidly accelerated fibrosarcoma polypeptides ARVINAS OPERATIONS, INC. (US) 2024-05-21 — — US disclosed
WO-2007085636-A1 REVERSIBLE THERMOCHROMIC COMPOSITIONS CIBA HOLDING INC. (CH) 2007-08-02 — — WO disclosed
US-20070078184-A1 Amino alcohol derivatives, medicinal composition containing the same, and use of these KISSEI PHARMACEUTICAL CO., LTD. (JP) 2007-04-05 — — US disclosed
US-20070078184-A1 Amino alcohol derivatives, medicinal composition containing the same, and use of these KISSEI PHARMACEUTICAL CO., LTD. (JP) 2007-04-05 — — US disclosed
WO-2006131465-A1 REVERSIBLY THERMOCHROMIC COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-12-14 — — WO disclosed
EP-1679304-A1 AMINO ALCOHOL DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND USE OF THESE Kissei Pharmaceutical Co., Ltd. (JP) 2006-07-12 — — EP disclosed
US-20060128807-A1 Amino alcohol derivatives, pharmaceutical compositions containing the same, and use thereof KISSEI PHARMACEUTICAL CO., LTD. (JP) 2006-06-15 — — US disclosed
EP-1593666-A1 AMINO ALCOHOL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND USE THEREOF Kissei Pharmaceutical Co., Ltd. (JP) 2005-11-09 — — EP disclosed
US-5563151-A PLATELET ACTIVATING FACTOR RECEPTOR ANTAGONISTS; ANTIINFLAMMATORY AGENTS, ANALGESICS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1996-10-08 — — US disclosed
EP-0623116-A1 AMINO ACID DERIVATIVES AS PAF-RECEPTOR ANTAGONISTS BRITISH BIO-TECHNOLOGY LIMITED (GB) 1994-11-09 — — EP disclosed
WO-1993014072-A1 AMINO ACID DERIVATIVES AS PAF-RECEPTOR ANTAGONISTS BRITISH BIO-TECHNOLOGY LIMITED (GB) 1993-07-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070078184-A1 Amino alcohol derivatives, medicinal composition containing the same, and use of these ADRB2, ADRA2A, ADRA1A LPL 2557/4885LIPG 3997/4885CA1 3861/4885
US-20060128807-A1 Amino alcohol derivatives, pharmaceutical compositions containing the same, and use thereof ADRB3, ADRA2C, ADRA1A LPL 1241/4885LIPG 3020/4885CA1 2886/4885
US-11986531-B2 Compounds and methods for the targeted degradation of rapidly accelerated fibrosarcoma polypeptides CRBN, ARAF, VHL LPL 2283/4885LIPG 1369/4885CA1 3341/4885
US-20260115296-A1 COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF RAPIDLY ACCELERATED FIBROSARCOMA POLYPEPTIDES CRBN, VHL, ADRM1 LPL 1736/4885LIPG 1464/4885CA1 3147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.