SCHEMBL5791176

SCHEMBL5791176

Clc1cccc(-c2c[nH]nn2)c1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.50
CNR2 P34972 10/20 0.43
NOTUM Q6P988 2/20 0.42
CNR1 P21554 2/20 0.41
CYP2D6 P10635 1/20 0.40
MAOA P21397 1/20 0.40
MAPK1 P28482 1/20 0.40
ADRA1A P35348 1/20 0.40
SCN4A P35499 1/20 0.40
BLM P54132 1/20 0.40
PMP22 Q01453 1/20 0.40
PDE3A Q14432 1/20 0.40
SCN5A Q14524 1/20 0.40
SCN9A Q15858 1/20 0.40
SCN2A Q99250 1/20 0.40
SCN3A Q9NY46 1/20 0.40
SCN10A Q9Y5Y9 1/20 0.40
NUDT1 P36639 2/20 0.39
LDHA P00338 1/20 0.37
P2RX7 Q99572 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1312553 0.85 LDHA (0.52) IDO1CNR2NOTUMLDHA
SCHEMBL3388195 0.82 IDO1 (0.53) IDO1CNR2LDHA
SCHEMBL2259968 0.79 LMNA (0.34) IDO1LDHA
SCHEMBL24217030 0.78 XDH (0.36) IDO1BLM
SCHEMBL2197897 0.78 ALDH1A1 (0.38) IDO1CYP2D6MAOAMAPK1BLM
SCHEMBL29628297 0.77 TSHR (0.46)
SCHEMBL29628499 0.74 SLC6A3 (0.48)
SCHEMBL1822947 0.73 ALDH1A1 (0.52) IDO1
SCHEMBL31653483 0.73 KDM4E (0.49)
SCHEMBL9563030 0.72 IDO1 (0.56) IDO1CNR2NOTUMCNR1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-222490871-U Screening device for dichlorobenzyl triazole preparation 湖北沃佳生物农业有限公司 2025-02-18 CN disclosed
WO-2006008238-A1 METHOD FOR SELECTIVE ACYLATION NOVO NORDISK A/S (DK) 2006-01-26 WO disclosed