Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4053266 | 0.82 | NPSR1 (0.42) | ALDH1A1LMNAHSD17B10GAAMEN1 | |
| SCHEMBL5591669 | 0.73 | NLRP3 (0.41) | ALDH1A1LMNAHSD17B10GAAMEN1 | |
| SCHEMBL5795696 | 0.71 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10GAASMN1; SMN2 | |
| SCHEMBL5793135 | 0.69 | PTGS2 (0.35) | ALDH1A1LMNAHSD17B10GAAMEN1 | |
| SCHEMBL5306513 | 0.69 | FAAH (0.49) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8906464 | 0.68 | PIN1 (0.39) | ALDH1A1LMNAHSD17B10GAAMEN1 | |
| SCHEMBL315410 | 0.67 | HSD17B10 (0.49) | ALDH1A1HSD17B10GAAMEN1KMT2A | |
| SCHEMBL25196732 | 0.66 | CYP26A1 (0.40) | ALDH1A1HSD17B10MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19716165 | 0.65 | CYP4F2 (0.40) | ALDH1A1LMNAHSD17B10GAAMEN1 | |
| SCHEMBL677833 | 0.64 | ALDH1A1 (0.43) | ALDH1A1LMNAHSD17B10GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007023018-A1 | 7-AMINO-6-TRIAZOLYL-1,2,4-TRIAZOLO[1,5-A]PYRIMIDINE COMPOUNDS AND THE USE THEREOF FOR CONTROLLING HARMFUL FUNGI | BASF AKTIENGESELLSCHAFT (DE) | 2007-03-01 | — | — | WO | disclosed |
| EP-1641788-A1 | PREPARATION OF N2-ALKYLATED 1,2,3-TRIAZOLES | Warner-Lambert Company LLC (US) | 2006-04-05 | — | — | EP | disclosed |
| WO-2005000841-A1 | PREPARATION OF N2-ALKYLATED 1,2,3-TRIAZOLES | WARNER-LAMBERT COMPANY LLC (US) | 2005-01-06 | — | — | WO | disclosed |
| US-20040266848-A1 | Preparation of N2-alkylated 1,2,3-triazoles | HADD MARK ALLEN (US) | 2004-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040266848-A1 | Preparation of N2-alkylated 1,2,3-triazoles | PPARA, PPARG, PPARD | ALDH1A1 2267/4885LMNA 1736/4885HSD17B10 1909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.