Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 5/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 3/20 | 0.39 |
| ▸ | PAM | P19021 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6080937 | 0.87 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1MAPK1PPARGPPARA | |
| SCHEMBL5795204 | 0.81 | KDM4E (0.55) | ALDH1A1L3MBTL1KDM4EHSD17B10PPARG | |
| SCHEMBL8324677 | 0.80 | L3MBTL1 (0.64) | ALDH1A1L3MBTL1MAPK1KDM4EKMT2A | |
| SCHEMBL11566628 | 0.80 | KDM4E (0.54) | ALDH1A1L3MBTL1KDM4EHSD17B10PPARG | |
| SCHEMBL5793096 | 0.80 | ALDH1A1 (0.64) | ALDH1A1L3MBTL1MAPK1PPARGPPARA | |
| SCHEMBL5795000 | 0.79 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1MAPK1PPARGPPARA | |
| SCHEMBL1009536 | 0.79 | KDM4E (0.53) | ALDH1A1L3MBTL1KDM4EHSD17B10PPARG | |
| SCHEMBL29224676 | 0.78 | KDM4E (0.58) | ALDH1A1L3MBTL1KDM4EHSD17B10PPARG | |
| SCHEMBL5795465 | 0.77 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1MAPK1PPARGPPARA | |
| SCHEMBL23241654 | 0.77 | TBXAS1 (0.44) | ALDH1A1L3MBTL1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006035157-A2 | SUBSTITUTED N-(BENZYL)PHENYLACETAMIDE DERIVATIVE COMPOUNDS, PREPARATION METHOD THEREOF AND USES OF SAME AS PPAR LIGANDS IN THE TREATMENT OF LIPID AND/OR GLUCIDIC DISORDERS | GENFIT (FR) | 2006-04-06 | — | — | WO | disclosed |