Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 4/20 | 0.30 |
| ▸ | GABRD | O14764 | 4/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.30 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.30 |
| ▸ | GABRE | P78334 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylglyoxal SCHEMBL9148515 | 0.86 | LMNA (0.57) | LMNATHRBALDH1A1BCHEACHE | |
| Bicarbonate SCHEMBL28895866 | 0.85 | LMNA (0.71) | LMNATHRBALDH1A1GABRPGABRD | |
| Bicarbonate SCHEMBL28942687 | 0.85 | LMNA (0.71) | LMNATHRBALDH1A1GABRPGABRD | |
| Bicarbonate SCHEMBL5374586 | 0.85 | LMNA (0.71) | LMNATHRBALDH1A1GABRPGABRD | |
| Acrylic Acid SCHEMBL1618847 | 0.84 | LMNA (0.55) | LMNAHCAR2THRBPPARAALDH1A1 | |
| SCHEMBL5582150 | 0.83 | LMNA (0.60) | LMNATHRB | |
| Acetic Acid SCHEMBL23907968 | 0.82 | LMNA (0.67) | LMNATHRBALDH1A1GABRPGABRD | |
| Acetic Acid SCHEMBL222953 | 0.82 | LMNA (0.67) | LMNATHRBALDH1A1GABRPGABRD | |
| Formic Acid SCHEMBL6366884 | 0.82 | LMNA (0.67) | LMNATHRB | |
| Bicarbonate SCHEMBL9453328 | 0.82 | LMNA (0.67) | LMNATHRBALDH1A1GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2916806-B1 | METHOD FOR STRAIGHTENING THE HAIR USING A COMPOSITION CONTAINING GLYOXYLIC ACID AND/OR A DERIVATIVE THEREOF | OREAL (FR) | 2018-12-26 | — | — | EP | claimed |
| US-20150305469-A1 | METHOD FOR STRAIGHTENING THE HAIR USING A COMPOSITION CONTAINING GLYOXYLIC ACID AND/OR A DERIVATIVE THEREOF | L'OREAL (FR) | 2015-10-29 | — | — | US | claimed |
| US-20150297488-A1 | COMPOSITION COMPRISING A DICARBONYL COMPOUND AND METHOD FOR SMOOTHING THE HAIR USING THIS COMPOSITION | L'OREAL (FR) | 2015-10-22 | — | — | US | claimed |
| WO-2003057687-A1 | METHODS FOR PREPARING DOXORUBICIN DERIVATIVES | ALBANY MOLECULAR RESEARCH, INC. (US) | 2003-07-17 | — | — | WO | claimed |
| WO-2003057896-A1 | METHODS FOR PREPARING ANTHRACYCLINONE DERIVATIVES AND ANTHRACYCLINONE DERIVATIVES PER SE | ALBANY MOLECULAR RESEARCH, INC. (US) | 2003-07-17 | — | — | WO | claimed |
| EP-0103945-B1 | SUBSTITUTED BENZENEDIOLS AND BENZODIOXINS | THE UPJOHN COMPANY (US) | 1988-04-20 | — | — | EP | claimed |
| US-4501892-A | Pyridyl benzenediols | THE UPJOHN COMPANY (US) | 1985-02-26 | — | — | US | claimed |
| EP-0103945-A2 | Substituted benzenediols and benzodioxins | THE UPJOHN COMPANY (US) | 1984-03-28 | — | — | EP | claimed |
| CN-113582915-A | Synthesis method of 4-substituted pyridine compound | 河南师范大学 | 2021-11-02 | — | — | CN | disclosed |
| US-20150305469-A1 | METHOD FOR STRAIGHTENING THE HAIR USING A COMPOSITION CONTAINING GLYOXYLIC ACID AND/OR A DERIVATIVE THEREOF | L'OREAL (FR) | 2015-10-29 | — | — | US | disclosed |
| WO-2006012277-A2 | BIOCATALYTIC PROCESS FOR PREPARING ENANTIOMERICALLY ENRICHED PRAMIPEXOLE | AMR TECHNOLOGY, INC. (US) | 2006-02-02 | — | — | WO | disclosed |
| WO-2003057896-A1 | METHODS FOR PREPARING ANTHRACYCLINONE DERIVATIVES AND ANTHRACYCLINONE DERIVATIVES PER SE | ALBANY MOLECULAR RESEARCH, INC. (US) | 2003-07-17 | — | — | WO | disclosed |
| US-5330739-A | Iodinated benzoyl acetals and ketals for x-ray imaging | STERLING WINTHROP INC. (US) | 1994-07-19 | — | — | US | disclosed |
| EP-0601617-A1 | Iodinated benzoyl acetals and ketals, and contrast agents containing them | NanoSystems L.L.C. (US) | 1994-06-15 | — | — | EP | disclosed |
| EP-0103945-B1 | SUBSTITUTED BENZENEDIOLS AND BENZODIOXINS | THE UPJOHN COMPANY (US) | 1988-04-20 | — | — | EP | disclosed |
| US-4501892-A | Pyridyl benzenediols | THE UPJOHN COMPANY (US) | 1985-02-26 | — | — | US | disclosed |
| EP-0107640-A1 | Dialkyl glyoxylate surfactants | MONSANTO COMPANY (US) | 1984-05-02 | — | — | EP | disclosed |
| EP-0103945-A2 | Substituted benzenediols and benzodioxins | THE UPJOHN COMPANY (US) | 1984-03-28 | — | — | EP | disclosed |
| US-4419258-A | Dialkyl glyoxylate surfactants | MONSANTO COMPANY (US) | 1983-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150297488-A1 | COMPOSITION COMPRISING A DICARBONYL COMPOUND AND METHOD FOR SMOOTHING THE HAIR USING THIS COMPOSITION | KRT18, SHH, SCO2 | LMNA 691/4885HCAR2 2936/4885THRB 3035/4885 |
| US-20150305469-A1 | METHOD FOR STRAIGHTENING THE HAIR USING A COMPOSITION CONTAINING GLYOXYLIC ACID AND/OR A DERIVATIVE THEREOF | GRHPR, HOGA1, CUTA | LMNA 668/4885HCAR2 186/4885THRB 1369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.