Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | RPS6KA2 | Q15349 | 3/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.33 |
| ▸ | DNASE1 | P24855 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5860460 | 0.75 | LMNA (0.49) | KDM4ELMNATDP1ALDH1A1MAPK1 | |
| SCHEMBL5272693 | 0.75 | ALDH1A1 (0.53) | KDM4ELMNAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL1486017 | 0.75 | TYMP (0.33) | — | |
| Ethylene SCHEMBL28028832 | 0.72 | KDM4E (0.51) | KDM4ELMNAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL294649 | 0.72 | PARP1 (0.36) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4348692 | 0.72 | ADRA1D (0.37) | — | |
| SCHEMBL4445914 | 0.70 | CYP1A2 (0.44) | LMNATDP1ALDH1A1MAPK1MAPT | |
| SCHEMBL28103828 | 0.70 | ALDH1A1 (0.46) | KDM4ELMNATDP1ALDH1A1MAPK1 | |
| SCHEMBL4885286 | 0.69 | BCAT2 (0.38) | KDM4ELMNATP53TDP1ALDH1A1 | |
| Hydrogen Sulfide SCHEMBL28104139 | 0.69 | ALDH1A1 (0.45) | KDM4ELMNATDP1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006070292-A2 | PYRIMIDINE COMPOUNDS AS ANTI-ICTOGENIC AND/OR ANTI-EPILEPTOGENIC AGENTS | QUEEN'S UNIVERSITY AT KINGSTON (US) | 2006-07-06 | — | — | WO | disclosed |