Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5043804 | 0.86 | ALDH1A1 (0.42) | KCNN4SLC6A2SLC6A4SLC6A3CES1 | |
| SCHEMBL13865453 | 0.77 | CYP2C19 (0.42) | KCNN4KIF11CES1OPRM1DRD3 | |
| SCHEMBL2822033 | 0.76 | KCNN4 (0.48) | KCNN4KIF11HDAC6CES1SMN1; SMN2 | |
| SCHEMBL9548452 | 0.75 | KIF11 (0.47) | KCNN4KIF11HDAC6CES1MEN1 | |
| SCHEMBL40498 | 0.75 | KIF11 (0.50) | KCNN4KIF11SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4842036 | 0.75 | SMN1; SMN2 (0.63) | SMN1; SMN2RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL3078236 | 0.73 | SMN1; SMN2 (0.49) | SMN1; SMN2MEN1KMT2AKDM4EPOLB | |
| SCHEMBL17965751 | 0.73 | KIF11 (0.48) | KCNN4KIF11HDAC6CES1MEN1 | |
| SCHEMBL13050382 | 0.73 | KIF11 (0.45) | KIF11 | |
| SCHEMBL889518 | 0.73 | HSD11B1 (0.47) | KCNN4KIF11HDAC6CES1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006057503-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPARϜ AND PPARα, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2006-06-01 | — | — | WO | disclosed |