Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.32 |
| ▸ | TACR3 | P29371 | 2/20 | 0.31 |
| ▸ | TACR2 | P21452 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.31 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALB | P02768 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5800516 | 0.93 | ABCB11 (0.35) | AKR1C3AKR1C2PTGS2SLC22A12PTGS1 | |
| SCHEMBL5554202 | 0.88 | TACR3 (0.33) | MAOBAKR1C3AKR1C2PTGS2PTGS1 | |
| SCHEMBL5559110 | 0.88 | MAOB (0.35) | MAOBAKR1C3AKR1C2PTGS2SLC22A12 | |
| SCHEMBL5799149 | 0.87 | AKR1C3 (0.43) | AKR1C3AKR1C2PTGS2PTGS1KDM4E | |
| SCHEMBL5814619 | 0.85 | CNR1 (0.38) | AKR1C3AKR1C2PTGS2ABCB11MAPT | |
| SCHEMBL5560487 | 0.85 | PDE2A (0.37) | MAOBAKR1C3AKR1C2PTGS2TACR3 | |
| SCHEMBL5560527 | 0.85 | PTGS2 (0.33) | MAOBAKR1C3AKR1C2PTGS2PTGS1 | |
| SCHEMBL5561193 | 0.82 | HPGD (0.34) | AKR1C3AKR1C2PTGS2LMNAKMT2A | |
| SCHEMBL5559667 | 0.82 | PTGS2 (0.35) | MAOBAKR1C3AKR1C2PTGS2SLC22A12 | |
| SCHEMBL5800412 | 0.82 | PTGS2 (0.46) | MAOBAKR1C3AKR1C2PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |