Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5559471 | 0.98 | PTGS2 (0.42) | PTGS2AKR1C3AKR1C2PTGS1 | |
| SCHEMBL5796692 | 0.93 | PTGS2 (0.37) | PTGS2AKR1C3AKR1C2CYP19A1PTGS1 | |
| SCHEMBL5559153 | 0.91 | TSHR (0.36) | PTGS2CYP19A1SMN1; SMN2 | |
| SCHEMBL5801342 | 0.91 | PTGS2 (0.35) | PTGS2AKR1C3AKR1C2CYP19A1 | |
| SCHEMBL5798160 | 0.91 | L3MBTL1 (0.37) | PTGS2CYP19A1 | |
| SCHEMBL5822558 | 0.90 | PTGS2 (0.34) | PTGS2CYP19A1 | |
| SCHEMBL5559074 | 0.89 | PTGS2 (0.40) | PTGS2 | |
| SCHEMBL5800837 | 0.89 | L3MBTL1 (0.37) | PTGS2 | |
| SCHEMBL5798701 | 0.88 | PTGS2 (0.45) | PTGS2AKR1C3AKR1C2CYP19A1SMN1; SMN2 | |
| SCHEMBL5797664 | 0.88 | LMNA (0.38) | PTGS2CYP19A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |