Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.30 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5796692 | 0.98 | PTGS2 (0.37) | PTGS2HSD11B1CYP19A1MEN1KMT2A | |
| SCHEMBL5822558 | 0.93 | PTGS2 (0.34) | PTGS2CYP19A1MGLL | |
| SCHEMBL5559471 | 0.93 | PTGS2 (0.42) | PTGS2AKR1C3AKR1C2 | |
| SCHEMBL5801005 | 0.91 | PTGS2 (0.44) | PTGS2CYP19A1AKR1C3AKR1C2 | |
| SCHEMBL5800837 | 0.91 | L3MBTL1 (0.37) | PTGS2HSD11B1MGLLALDH1A1 | |
| SCHEMBL5559153 | 0.90 | TSHR (0.36) | PTGS2HSD11B1CYP19A1KMT2AALDH1A1 | |
| SCHEMBL5554521 | 0.90 | LMNA (0.38) | HSD11B1MEN1KMT2AALDH1A1AKR1C3 | |
| SCHEMBL5558388 | 0.89 | PTGS2 (0.35) | PTGS2HSD11B1CYP19A1MEN1KMT2A | |
| SCHEMBL5798160 | 0.89 | L3MBTL1 (0.37) | PTGS2HSD11B1CYP19A1MGLLALDH1A1 | |
| SCHEMBL5797664 | 0.88 | LMNA (0.38) | PTGS2HSD11B1CYP19A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |