Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27565960 | 0.81 | NPC1 (0.48) | ALDH1A1TDP1L3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL10801072 | 0.77 | TDP1 (0.62) | MAPK1ALDH1A1TDP1L3MBTL1TSHR | |
| SCHEMBL96720 | 0.76 | HTR7 (0.47) | MAPK1ALDH1A1L3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL1156407 | 0.74 | MAPK1 (0.58) | MAPK1ALDH1A1TDP1L3MBTL1TSHR | |
| SCHEMBL1847263 | 0.74 | ALDH1A1 (0.58) | MAPK1ALDH1A1TDP1L3MBTL1TSHR | |
| SCHEMBL10467229 | 0.74 | MAPK1 (0.58) | MAPK1ALDH1A1TDP1L3MBTL1TSHR | |
| SCHEMBL7415972 | 0.73 | DAO (0.39) | ALDH1A1TDP1HPGDMEN1KMT2A | |
| SCHEMBL4220489 | 0.72 | TDP1 (0.56) | MAPK1ALDH1A1TDP1L3MBTL1TSHR | |
| SCHEMBL1615073 | 0.72 | PKM (0.70) | MAPK1ALDH1A1TDP1L3MBTL1TSHR | |
| SCHEMBL514661 | 0.71 | APP (0.42) | ALDH1A1RAB9ANPC1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006093518-A2 | THIENYL COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS | APATH, LLC (US) | 2006-09-08 | — | — | WO | disclosed |