Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRAP1 | Q12931 | 3/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.53 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.47 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.43 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29549804 | 1.00 | TRAP1 (0.53) | TRAP1HSP90AA1HSP90B1ALDH1A1HSD17B10 | |
| SCHEMBL18552099 | 0.90 | ALDH1A1 (0.53) | TRAP1HSP90AA1ALDH1A1HSD17B10LTB4R | |
| SCHEMBL5818018 | 0.81 | ADORA1 (0.55) | ALDH1A1HSD17B10LTB4RHSP90AB1ADORA1 | |
| SCHEMBL27612520 | 0.76 | LTB4R (0.53) | TRAP1HSP90AA1ALDH1A1HSD17B10LTB4R | |
| SCHEMBL10488901 | 0.75 | DHFR (0.62) | — | |
| SCHEMBL6942102 | 0.74 | ALDH1A1 (0.46) | ALDH1A1HSD17B10LTB4RTAAR1SLC6A4 | |
| SCHEMBL27357112 | 0.74 | HSP90AB1 (0.54) | TRAP1ALDH1A1HSD17B10LTB4RHSP90AB1 | |
| SCHEMBL5819368 | 0.74 | MAPT (0.48) | ALDH1A1HSD17B10 | |
| SCHEMBL7797433 | 0.73 | PDE5A (0.48) | TRAP1HSP90AA1ALDH1A1HSD17B10LTB4R | |
| SCHEMBL14201605 | 0.72 | MPO (0.47) | HSP90AA1ALDH1A1HSD17B10LTB4RMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3952849-A2 | COMPOSITIONS AND METHODS FOR INCREASING MUSCLE MASS AND OXIDATIVE METABOLISM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-02-16 | — | — | EP | disclosed |
| WO-2020210521-A2 | COMPOSITIONS AND METHODS FOR INCREASING MUSCLE MASS AND OXIDATIVE METABOLISM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-10-15 | — | — | WO | disclosed |
| WO-2006078886-A2 | COMPOUNDS AND COMPOSITIONS AS WNT SIGNALING PATHWAY MODULATORS | IRM LLC (BM) | 2006-07-27 | — | — | WO | disclosed |