Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5808461 | 0.86 | MAPT (0.57) | MEN1KMT2AMAPTKDM4ELIMK1 | |
| SCHEMBL5808462 | 0.80 | MAPT (0.39) | MEN1KMT2AMAPTKDM4ELIMK1 | |
| SCHEMBL31156481 | 0.76 | KDM4E (0.64) | TSHRMEN1KMT2AMAPTKDM4E | |
| SCHEMBL31156511 | 0.76 | KDM4E (0.64) | TSHRMEN1KMT2AMAPTKDM4E | |
| SCHEMBL5729872 | 0.76 | MEN1 (0.67) | MEN1KMT2AMAPTKDM4ELIMK1 | |
| SCHEMBL5730603 | 0.76 | LIMK1 (0.61) | TSHRMEN1KMT2AMAPTKDM4E | |
| SCHEMBL5731488 | 0.75 | IKBKB (0.69) | MEN1KMT2AMAPTKDM4ELIMK1 | |
| SCHEMBL5808459 | 0.75 | MEN1 (0.46) | MEN1KMT2AMAPTKDM4ETP53 | |
| SCHEMBL5806520 | 0.74 | MAPT (0.45) | MEN1KMT2AMAPTKDM4ELIMK1 | |
| SCHEMBL5820468 | 0.74 | MAPT (0.45) | MEN1KMT2AMAPTKDM4ELIMK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006100095-A1 | SUBSTITUTED CARBOXAMIDES METHOD FOR PRODUCTION AND USE THEREOF AS TNF-ALPHA RELEASE INHIBITORS | CURACYTE DISCOVERY GMBH (DE) | 2006-09-28 | — | — | WO | claimed |