Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5808459 | 0.89 | MEN1 (0.46) | MAPTKMT2AMEN1KDM4ETP53 | |
| SCHEMBL5806520 | 0.88 | MAPT (0.45) | MAPTKMT2AMEN1KDM4EIKBKB | |
| SCHEMBL5820468 | 0.88 | MAPT (0.45) | MAPTKMT2AMEN1KDM4EIKBKB | |
| SCHEMBL5808457 | 0.86 | MAPT (0.43) | MAPTKMT2AMEN1KDM4EIKBKB | |
| SCHEMBL5816926 | 0.86 | MAPT (0.43) | MAPTKMT2AMEN1KDM4EIKBKB | |
| SCHEMBL5805727 | 0.86 | TSHR (0.47) | MAPTKMT2AMEN1KDM4EIKBKB | |
| SCHEMBL5806498 | 0.86 | MAPT (0.43) | MAPTKMT2AMEN1KDM4EIKBKB | |
| SCHEMBL5809433 | 0.85 | MEN1 (0.43) | MAPTKMT2AMEN1IKBKBALDH1A1 | |
| SCHEMBL2856060 | 0.84 | MAPT (0.42) | MAPTKMT2AMEN1KDM4ERAB9A | |
| SCHEMBL5805681 | 0.84 | MAPT (0.46) | MAPTKMT2AMEN1KDM4EIKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006100095-A1 | SUBSTITUTED CARBOXAMIDES METHOD FOR PRODUCTION AND USE THEREOF AS TNF-ALPHA RELEASE INHIBITORS | CURACYTE DISCOVERY GMBH (DE) | 2006-09-28 | — | — | WO | claimed |