SCHEMBL5807173

SCHEMBL5807173

O=S(=O)(Oc1cccnc1)c1cc(I)c2occc2c1

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 4/20 0.38
CA2 P00918 6/20 0.36
CA12 O43570 5/20 0.36
CA1 P00915 2/20 0.35
ALDH1A1 P00352 5/20 0.34
HPGD P15428 3/20 0.34
TDP1 Q9NUW8 2/20 0.34
MAPT P10636 2/20 0.34
LMNA P02545 2/20 0.33
DAO P14920 1/20 0.33
PTGS2 P35354 1/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
HTT P42858 2/20 0.33
KDM4E B2RXH2 1/20 0.33
HTR6 P50406 1/20 0.32
FFAR4 Q5NUL3 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5802772 0.78 HTR6 (0.39) HTR6
SCHEMBL5803281 0.78 LMNA (0.39) CA2CA12TDP1MAPTLMNA
Hydrochloric Acid SCHEMBL5803718 0.77 HTR6 (0.38) HTR6
Trifluoroacetic Acid SCHEMBL5824147 0.72 CDK2 (0.38) ALDH1A1HTR6
SCHEMBL11294092 0.70 TDP1 (0.51) CA9CA2CA12CA1ALDH1A1
SCHEMBL5954926 0.70 MAPT (0.38) CA2CA12ALDH1A1MAPTLMNA
SCHEMBL1062600 0.69 CA1 (0.33) CA9CA2CA12CA1ALDH1A1
SCHEMBL3059477 0.67 ALDH1A1 (0.53) ALDH1A1HPGDTDP1MAPTLMNA
SCHEMBL31328185 0.65 NAPRT (0.52) CA9CA2CA12CA1ALDH1A1
SCHEMBL8986603 0.65 NAPRT (0.52) CA9CA2CA12CA1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060142269-A1 New compounds BIOVITRUM AB (SE) 2006-06-29 US disclosed
WO-2006062481-A1 NEW BENZOFURAN DERIVATIVES AND THEIR USE IN THE TREATMENT OF OBESITY, TYPE II DIABETES AND CNS DISORDERS . BIOVITRUM AB (SE) 2006-06-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060142269-A1 New compounds GPR119, GLP1R, IAPP CA9 3170/4885CA2 2927/4885CA12 2791/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.