SCHEMBL3059477

SCHEMBL3059477

Cc1ccc(S(=O)(=O)Oc2cccnc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.53
KMT2A Q03164 5/20 0.53
MEN1 O00255 3/20 0.53
MAPT P10636 3/20 0.53
LMNA P02545 4/20 0.51
POLB P06746 1/20 0.48
EGFR P00533 1/20 0.47
PTGS2 P35354 1/20 0.47
KEAP1 Q14145 1/20 0.47
NFE2L2 Q16236 1/20 0.47
HPGD P15428 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
HTT P42858 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11294092 0.85 TDP1 (0.51) ALDH1A1MAPTLMNAPTGS2HPGD
SCHEMBL22558457 0.84 ALDH1A1 (0.53) ALDH1A1KMT2AMEN1MAPTLMNA
SCHEMBL9547096 0.83 ADRB2 (0.45) ALDH1A1KMT2AMAPTLMNAPOLB
SCHEMBL29575610 0.81 KMT2A (0.48) ALDH1A1KMT2AMEN1MAPTLMNA
SCHEMBL9598330 0.80 ALDH1A1 (0.50) ALDH1A1KMT2AMEN1MAPTLMNA
SCHEMBL6937180 0.80 KMT2A (0.55) ALDH1A1KMT2AMEN1MAPTLMNA
SCHEMBL346667 0.79 HTT (0.59) ALDH1A1KMT2AMEN1MAPTLMNA
SCHEMBL28566928 0.79 KMT2A (0.46) ALDH1A1KMT2AMEN1MAPTLMNA
SCHEMBL10684102 0.79 MEN1 (0.49) ALDH1A1KMT2AMEN1MAPTKEAP1
SCHEMBL21618283 0.78 ALDH1A1 (0.44) ALDH1A1KMT2AMEN1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0011460-B1 PEROXYGEN BLEACHING AND COMPOSITIONS THEREFOR FMC Corporation (US) 1982-09-29 EP claimed
EP-0011460-A1 Peroxygen bleaching and compositions therefor FMC Corporation (US) 1980-05-28 EP claimed
US-20230284471-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-09-07 US disclosed
US-11542270-B2 BCKDK inhibitors PFIZER INC. (US) 2023-01-03 US disclosed
US-20210024536-A1 BCKDK INHIBITORS PFIZER INC. (US) 2021-01-28 US disclosed
US-9983476-B2 Resin composition including novel polymer and organic film using the same SAMSUNG SDI CO., LTD. (KR) 2018-05-29 US disclosed
US-20170139323-A1 Resin Composition Including Novel Polymer and Organic Film Using the Same SAMSUNG SDI CO., LTD. (KR) 2017-05-18 US disclosed
EP-1581467-B1 LIGANDS FOR METALS AND IMPROVED METAL-CATALYZED PROCESSES BASED THEREON MASSACHUSETTS INST TECHNOLOGY (US) 2016-10-12 EP disclosed
EP-2583958-B1 Ligands for metals and improved metal-catalyzed processes based thereon MASSACHUSETTS INST TECHNOLOGY (US) 2016-08-10 EP disclosed
EP-2173716-B1 A PROCESS FOR THE PALLADIUM-CATALYZED COUPLING OF TERMINAL ALKYNES WITH HETEROARYL TOSYLATES AND HETEROARYL BENZENESULFONATES SANOFI SA (FR) 2014-03-19 EP disclosed
CN-101687796-B Palladium-catalyzed coupling reaction of terminal alkynes with heteroaryltosylates and heteroarylbenzenesulfonates SANOFI AVENTIS SPA 2013-08-14 CN disclosed
EP-1167372-B1 2,2-(Diaryl)vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst TAKASAGO PERFUMERY CO LTD (JP) 2003-12-10 EP disclosed
US-6455720-B1 AS CATALYSTS TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-09-24 US disclosed
US-20020058837-A1 2,2 (Diarlyl) Vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-05-16 US disclosed
US-6365776-B1 FROM ORGANOHALOGEN COMPOUND AND AMINE USING PALLADIUM COMPOUND CATALYST AND PROMOTER TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-04-02 US disclosed
US-20020035295-A1 PROCESS FOR PRODUCING AROMATIC AMINES TAKASAGO INTERNATIONAL CORPORATION 2002-03-21 US disclosed
EP-1167372-A1 2,2-(Diaryl)vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst Takasago International Corporation (JP) 2002-01-02 EP disclosed
EP-0011460-B1 PEROXYGEN BLEACHING AND COMPOSITIONS THEREFOR FMC Corporation (US) 1982-09-29 EP disclosed
US-4215003-A INCLUDING HETEROCYCLIC SULFONATE ESTERS OF AN ALKANE- OR ARYLSULFONIC ACID AS ACTIVATORS; LOW TEMPERATURE FMC CORPORATION (US) 1980-07-29 US disclosed
EP-0011460-A1 Peroxygen bleaching and compositions therefor FMC Corporation (US) 1980-05-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020035295-A1 PROCESS FOR PRODUCING AROMATIC AMINES TYR, DDC, PNMT ALDH1A1 1669/4885KMT2A 359/4885MEN1 1606/4885
US-20020058837-A1 2,2 (Diarlyl) Vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst DDT, PDCD11, PLD2 ALDH1A1 2369/4885KMT2A 170/4885MEN1 2881/4885
US-11542270-B2 BCKDK inhibitors BCKDK, PDK4, PDK3 ALDH1A1 272/4885KMT2A 2155/4885MEN1 4252/4885
US-20210024536-A1 BCKDK INHIBITORS BCKDK, PDK4, PDK3 ALDH1A1 272/4885KMT2A 2155/4885MEN1 4252/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.