Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | LITAF | Q99732 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5806831 | 0.87 | MAOA (0.35) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL5805951 | 0.86 | MAOA (0.34) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5808673 | 0.85 | DYRK1A (0.44) | MEN1KMT2AATMDYRK1AACSS2 | |
| SCHEMBL5810191 | 0.85 | TDP1 (0.33) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5809117 | 0.84 | DYRK1A (0.35) | KDM4EALDH1A1MAPTDYRK1AACSS2 | |
| Hydrochloric Acid SCHEMBL5811743 | 0.83 | TDP1 (0.32) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5806362 | 0.82 | DYRK1A (0.46) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5810449 | 0.81 | KMT2A (0.38) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5807848 | 0.80 | TRPA1 (0.41) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL5810298 | 0.80 | ACHE (0.48) | DYRK1AACSS2MAOARPS6KA5HASPIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025717-A1 | PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | claimed |
| WO-2006025717-A1 | PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | disclosed |