Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 8/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5805681 | 0.88 | MAPT (0.46) | KMT2AMAPTMEN1CHRM4KDM4E | |
| SCHEMBL5808461 | 0.82 | MAPT (0.57) | KMT2AMAPTMEN1CHRM4KDM4E | |
| SCHEMBL5806498 | 0.81 | MAPT (0.43) | KMT2AMAPTMEN1CHRM4KDM4E | |
| SCHEMBL5809588 | 0.80 | MAPT (0.39) | KMT2AMAPTMEN1CHRM4PIM1 | |
| SCHEMBL5808459 | 0.79 | MEN1 (0.46) | KMT2AMAPTMEN1CHRM4KDM4E | |
| SCHEMBL5806520 | 0.78 | MAPT (0.45) | KMT2AMAPTMEN1CHRM4KDM4E | |
| SCHEMBL5809433 | 0.78 | MEN1 (0.43) | KMT2AMAPTMEN1ALDH1A1GAA | |
| SCHEMBL5820468 | 0.78 | MAPT (0.45) | KMT2AMAPTMEN1CHRM4KDM4E | |
| SCHEMBL5808457 | 0.76 | MAPT (0.43) | KMT2AMAPTMEN1KDM4EALDH1A1 | |
| SCHEMBL5816926 | 0.76 | MAPT (0.43) | KMT2AMAPTMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006100095-A1 | SUBSTITUTED CARBOXAMIDES METHOD FOR PRODUCTION AND USE THEREOF AS TNF-ALPHA RELEASE INHIBITORS | CURACYTE DISCOVERY GMBH (DE) | 2006-09-28 | — | — | WO | disclosed |