Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.36 |
| ▸ | SLC6A12 | P48065 | 3/20 | 0.34 |
| ▸ | SLC6A11 | P48066 | 3/20 | 0.34 |
| ▸ | SLC6A13 | Q9NSD5 | 3/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30477996 | 0.84 | HSD11B1 (0.46) | HSD11B1GRM2GRM5GRM1ALDH1A1 | |
| SCHEMBL5826784 | 0.77 | GRIN2D (0.44) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL5487038 | 0.77 | HSD11B1 (0.48) | HSD11B1SLC6A12SLC6A11SLC6A13GRM2 | |
| SCHEMBL26217994 | 0.70 | ALDH1A1 (0.38) | HSD11B1THRBCYP2C9ALDH1A1POLB | |
| SCHEMBL6559876 | 0.69 | HSD11B1 (0.33) | HSD11B1ALDH1A1 | |
| SCHEMBL5822452 | 0.68 | THRB (0.36) | HSD11B1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3022337 | 0.68 | KDM4E (0.39) | HSD11B1THRBCYP2C9ALDH1A1KDM4E | |
| Glycine SCHEMBL28006238 | 0.67 | GLRA1 (0.46) | HSD11B1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL703301 | 0.67 | EPHX2 (0.38) | HSD11B1ALDH1A1POLBEPHX2 | |
| SCHEMBL19151709 | 0.66 | HSD11B1 (0.38) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006097774-A1 | SYNTHETIC PEPTIDES CONTAINING UNNATURAL ADAMANTANE-RELATED AMINO ACIDS FOR USE AS ANTITUMOUR DRUGS | RUDJER BOSKOVIC INSTITUTE (HR) | 2006-09-21 | — | — | WO | disclosed |