Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6213 | 0.89 | MAOB (0.55) | MMP2MMP9ADAM17MAOBFFAR1 | |
| SCHEMBL5637 | 0.89 | MMP2 (0.50) | MMP2MMP9MMP14ADAM17MRGPRX4 | |
| SCHEMBL6159 | 0.85 | PDE4A (0.43) | ALOX5PTPRZ1RXRARXRBPARP10 | |
| SCHEMBL5798 | 0.83 | CYP27B1 (0.46) | ADAM17MAOBALOX5RXRARXRB | |
| SCHEMBL5810 | 0.78 | MMP1 (0.48) | MMP1MMP2MMP9MMP14ADAM17 | |
| SCHEMBL11898794 | 0.77 | ADAMTS4 (0.47) | ADAM17ALOX5CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL6074 | 0.77 | CA12 (0.46) | MMP9 | |
| SCHEMBL11899995 | 0.76 | PARP10 (0.48) | ALOX5ALDH1A1PARP10PPARG | |
| SCHEMBL27678084 | 0.74 | RXRA (0.51) | MMP1MMP2MMP9MMP14ADAM17 | |
| SCHEMBL12050 | 0.72 | ACACB (0.43) | ALDH1A1FFAR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488489-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | Pfizer Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011045703-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2011-04-21 | — | — | WO | disclosed |