Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPRB | P23467 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | CDC25A | P30304 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5812 | 0.89 | MMP1 (0.47) | MAOBFFAR1PPARGMMP2MMP9 | |
| SCHEMBL5798 | 0.85 | CYP27B1 (0.46) | MAOBADAMTS4MMP13ADAM17 | |
| SCHEMBL6159 | 0.85 | PDE4A (0.43) | FFAR1 | |
| SCHEMBL5637 | 0.81 | MMP2 (0.50) | MAOBFFAR1MMP2MMP9ADAM17 | |
| SCHEMBL6211 | 0.78 | MAOB (0.57) | MAOBFFAR1PPARGMMP2MMP9 | |
| SCHEMBL11898794 | 0.77 | ADAMTS4 (0.47) | ADAMTS4MMP13ADAM17 | |
| SCHEMBL6074 | 0.77 | CA12 (0.46) | MMP9MMP13 | |
| SCHEMBL11899995 | 0.76 | PARP10 (0.48) | PPARG | |
| SCHEMBL9475309 | 0.75 | ALOX5 (0.72) | MAOBFFAR1PPARG | |
| SCHEMBL12050 | 0.75 | ACACB (0.43) | FFAR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488489-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | Pfizer Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011045703-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2011-04-21 | — | — | WO | disclosed |