Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5812355 | 0.88 | PLA2G2A (0.39) | LMNAALDH1A1PLA2G2AKMT2ATHRA | |
| SCHEMBL5812476 | 0.86 | LTB4R (0.34) | ALDH1A1PLA2G2AKMT2ATHRATHRB | |
| SCHEMBL5811105 | 0.85 | POLB (0.35) | PLA2G2ATHRATHRB | |
| SCHEMBL5807179 | 0.81 | KMT2A (0.33) | LMNAALDH1A1PLA2G2AKMT2ATHRA | |
| SCHEMBL5810585 | 0.81 | PLA2G2A (0.41) | PLA2G2AKMT2ATHRATHRB | |
| SCHEMBL14106844 | 0.80 | XDH (0.35) | THRATHRB | |
| SCHEMBL5808083 | 0.79 | LTB4R (0.34) | ALDH1A1PLA2G2AKMT2ATHRATHRB | |
| SCHEMBL5808071 | 0.79 | LTB4R (0.34) | ALDH1A1PLA2G2AKMT2ATHRATHRB | |
| SCHEMBL5809194 | 0.78 | THRA (0.41) | PLA2G2AKMT2ATHRATHRB | |
| SCHEMBL5812353 | 0.77 | LTB4R (0.36) | PLA2G2AKMT2ATHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006046683-A1 | THIAZOLYLBENZOFURAN DERIVATIVES AS LEUKOTRIENE AND PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | ASTELLAS PHARMA INC. (JP) | 2006-05-04 | — | — | WO | disclosed |