Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASR | P41180 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 2/20 | 0.42 |
| ▸ | FNTB | P49356 | 2/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5819200 | 0.95 | ALDH1A1 (0.56) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL5801209 | 0.80 | TRPM8 (0.47) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL5802781 | 0.78 | TRPM8 (0.45) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL27602815 | 0.74 | NPC1 (0.59) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9871496 | 0.74 | RAB9A (0.63) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL4566801 | 0.72 | TRPM8 (0.53) | NPC1ALDH1A1MAPTSMN1; SMN2TRPM8 | |
| SCHEMBL3568466 | 0.72 | TRPM8 (0.41) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11050841 | 0.71 | TSHR (0.64) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL4554499 | 0.70 | HSD17B10 (0.60) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL19707507 | 0.70 | TSHR (0.57) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006063113-A2 | UREAS AS FACTOR XA INHIBITORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2006-06-15 | — | — | WO | claimed |