Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL582869 | 0.79 | IAPP (0.35) | MTNR1AALDH1A1 | |
| SCHEMBL8954003 | 0.68 | GFER (0.45) | ALDH1A1 | |
| SCHEMBL15733744 | 0.65 | TAAR1 (0.40) | — | |
| SCHEMBL17937687 | 0.65 | TAAR1 (0.40) | ALDH1A1 | |
| SCHEMBL927507 | 0.65 | LMNA (0.33) | — | |
| SCHEMBL17937753 | 0.65 | TAAR1 (0.40) | — | |
| SCHEMBL706073 | 0.64 | IDO1 (0.38) | ALDH1A1 | |
| SCHEMBL12081441 | 0.64 | MTNR1A (0.39) | MTNR1AALDH1A1 | |
| SCHEMBL15733772 | 0.64 | — | — | |
| SCHEMBL18199327 | 0.64 | ALDH1A1 (0.44) | BACE1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2681272-B1 | RUBBER COMPOSITION CONTAINING BLOCKED MERCAPTOSILANES AND ARTICLES MADE THEREFROM | MOMENTIVE PERFORMANCE MAT INC (US) | 2015-07-08 | — | — | EP | claimed |
| EP-2681272-A1 | RUBBER COMPOSITION CONTAINING BLOCKED MERCAPTOSILANES AND ARTICLES MADE THEREFROM | Momentive Performance Materials Inc. (US) | 2014-01-08 | — | — | EP | claimed |
| US-8592506-B2 | Tire compositions and components containing blocked mercaptosilane coupling agent | CONTINENTAL AG (DE) | 2013-11-26 | — | — | US | claimed |
| US-8383850-B2 | Blocked mercaptosilane coupling agents, process for making and uses in rubber | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2013-02-26 | — | — | US | claimed |
| WO-2012118918-A1 | RUBBER COMPOSITION CONTAINING BLOCKED MERCAPTOSILANES AND ARTICLES MADE THEREFROM | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2012-09-07 | — | — | WO | claimed |
| US-20120225231-A1 | RUBBER COMPOSITION CONTAINING BLOCKED MERCAPTOSILANES AND ARTICLES MADE THEREFROM | MOMENTIVE PERFORMANCE MATERIALS, INC (US) | 2012-09-06 | — | — | US | claimed |
| EP-2094741-B1 | TIRE COMPOSITIONS AND COMPONENTS CONTAINING BLOCKED MERCAPTOSILANE COUPLING AGENT | CONTINENTAL REIFEN DEUTSCHLAND (DE) | 2012-02-15 | — | — | EP | claimed |
| US-20100256273-A1 | Blocked Mercaptosilane Coupling Agents, Process for Making and Uses in Rubber | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2010-10-07 | — | — | US | claimed |
| US-7781606-B2 | Blocked mercaptosilane coupling agents, process for making and uses in rubber | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2010-08-24 | — | — | US | claimed |
| EP-2094741-A2 | TIRE COMPOSITIONS AND COMPONENTS CONTAINING BLOCKED MERCAPTOSILANE COUPLING AGENT | Continental AG (DE) | 2009-09-02 | — | — | EP | claimed |
| WO-2008083246-A2 | TIRE COMPOSITIONS AND COMPONENTS CONTAINING BLOCKED MERCAPTOSILANE COUPLING AGENT | CONTINENTAL AG (DE) | 2008-07-10 | — | — | WO | claimed |
| US-20080161590-A1 | Blocked mercaptosilane coupling agents, process for making and uses in rubber | MOMENTIVE PERFORMANCE MATERIALS INC. | 2008-07-03 | — | — | US | claimed |
| US-20080161486-A1 | TIRE COMPOSITIONS AND COMPONENTS CONTAINING BLOCKED MERCAPTOSILANE COUPLING AGENT | CONTINENTAL AG (DE) | 2008-07-03 | — | — | US | claimed |
| US-9447262-B2 | Rubber composition containing blocked mercaptosilanes and articles made therefrom | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2016-09-20 | — | — | US | disclosed |
| EP-2681272-B1 | RUBBER COMPOSITION CONTAINING BLOCKED MERCAPTOSILANES AND ARTICLES MADE THEREFROM | MOMENTIVE PERFORMANCE MAT INC (US) | 2015-07-08 | — | — | EP | disclosed |
| EP-2114960-B1 | BLOCKED MERCAPTOSILANE COUPLING AGENTS, PROCESS FOR MAKING AND USE IN RUBBER COMPOSITIONS | MOMENTIVE PERFORMANCE MAT INC (US) | 2014-07-02 | — | — | EP | disclosed |
| EP-2114960-A1 | BLOCKED MERCAPTOSILANE COUPLING AGENTS, PROCESS FOR MAKING AND USE IN RUBBER COMPOSITIONS | Momentive Performance Materials Inc. (US) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008085415-A1 | BLOCKED MERCAPTOSILANE COUPLING AGENTS, PROCESS FOR MAKING AND USE IN RUBBER COMPOSITIONS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2008-07-17 | — | — | WO | disclosed |
| US-20080161590-A1 | Blocked mercaptosilane coupling agents, process for making and uses in rubber | MOMENTIVE PERFORMANCE MATERIALS INC. | 2008-07-03 | — | — | US | disclosed |
| US-20080161486-A1 | TIRE COMPOSITIONS AND COMPONENTS CONTAINING BLOCKED MERCAPTOSILANE COUPLING AGENT | CONTINENTAL AG (DE) | 2008-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161590-A1 | Blocked mercaptosilane coupling agents, process for making and uses in rubber | TST, MSN, SRMS | BACE1 4772/4885MTNR1A 3978/4885ADORA3 4276/4885 |
| US-20100256273-A1 | Blocked Mercaptosilane Coupling Agents, Process for Making and Uses in Rubber | TST, MSN, SRMS | BACE1 4772/4885MTNR1A 3978/4885ADORA3 4276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.