Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.33 |
| ▸ | MAT2A | P31153 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5820890 | 0.84 | ALDH1A1 (0.41) | ALDH1A1POLBL3MBTL1MAPTKDM4E | |
| SCHEMBL5820993 | 0.83 | ALDH1A1 (0.41) | ALDH1A1POLBL3MBTL1MAPTKDM4E | |
| SCHEMBL5818149 | 0.76 | ESR1 (0.34) | ALDH1A1POLBL3MBTL1MAPTKDM4E | |
| SCHEMBL5823518 | 0.74 | G6PD (0.57) | ALDH1A1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL5817609 | 0.71 | MAPK13 (0.39) | ALDH1A1L3MBTL1LMNAESR1MEN1 | |
| SCHEMBL5821416 | 0.71 | AOC3 (0.42) | ALDH1A1L3MBTL1MAPTGAASMN1; SMN2 | |
| SCHEMBL5821434 | 0.68 | ALDH1A1 (0.42) | ALDH1A1POLBMAPTKDM4ELMNA | |
| SCHEMBL5820968 | 0.68 | CA2 (0.38) | GAAKMT2A | |
| SCHEMBL14223774 | 0.67 | L3MBTL1 (0.40) | ALDH1A1POLBL3MBTL1MAPTKDM4E | |
| SCHEMBL5821281 | 0.66 | PTGS2 (0.38) | MAPTGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006129181-A2 | PREPARATION OF 4-PYRIMIDONE DERIVATIVES FOR TREATING INFLAMMATORY DISEASES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2006-12-07 | — | — | WO | disclosed |