Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 11/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.43 |
| ▸ | HPGD | P15428 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5823657 | 0.84 | ALDH1A1 (0.46) | MAPTHPGDLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL5796946 | 0.82 | MTNR1A (0.43) | MAPTHPGDLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL5795637 | 0.79 | HDAC1 (0.37) | MAPTKDM4EHPGDLMNASMN1; SMN2 | |
| SCHEMBL5808415 | 0.76 | MAPT (0.43) | MAPTKDM4EHPGDLMNASMN1; SMN2 | |
| SCHEMBL5797087 | 0.76 | CHRM2 (0.53) | PTGER4MAPTKDM4EHPGDLMNA | |
| SCHEMBL5799640 | 0.76 | MAPT (0.52) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL5799659 | 0.76 | MTNR1A (0.41) | MAPTKDM4ELMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL5799923 | 0.75 | GCGR (0.43) | MAPTKDM4EHPGDLMNAALDH1A1 | |
| SCHEMBL5808242 | 0.75 | P2RX3 (0.45) | MAPTKDM4EHPGDLMNASMN1; SMN2 | |
| SCHEMBL5808245 | 0.75 | P2RX3 (0.45) | MAPTKDM4EHPGDLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |