SCHEMBL582647

SCHEMBL582647

CCC(C(=O)Cl)c1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.56
HSD17B10 Q99714 1/20 0.56
KCNQ2 O43526 2/20 0.54
ALDH1A1 P00352 3/20 0.51
POLB P06746 1/20 0.51
CRHBP P24387 2/20 0.50
CRHR2 Q13324 2/20 0.50
HTT P42858 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
MAPT P10636 3/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
GAA P10253 2/20 0.49
KDM4A O75164 1/20 0.49
BCHE P06276 1/20 0.49
NPSR1 Q6W5P4 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6410341 1.00 LMNA (0.56) LMNAHSD17B10KCNQ2ALDH1A1POLB
SCHEMBL16820449 1.00 LMNA (0.56) LMNAHSD17B10KCNQ2ALDH1A1POLB
SCHEMBL27620277 0.89 PTGS2 (0.50) LMNAHSD17B10KCNQ2ALDH1A1POLB
SCHEMBL4935067 0.85 LMNA (0.61) LMNAHSD17B10KCNQ2ALDH1A1POLB
SCHEMBL20553663 0.84 CTSS (0.49) LMNAHSD17B10KCNQ2ALDH1A1MAPT
SCHEMBL971454 0.84 CYP2C19 (0.48) LMNAHSD17B10KCNQ2ALDH1A1POLB
SCHEMBL8728377 0.84 MAPT (0.45) LMNAHSD17B10KCNQ2ALDH1A1POLB
SCHEMBL1715 0.83 LMNA (0.59) LMNAHSD17B10KCNQ2ALDH1A1POLB
SCHEMBL65737 0.83 LMNA (0.59) LMNAHSD17B10KCNQ2ALDH1A1POLB
SCHEMBL20769804 0.83 LMNA (0.59) LMNAHSD17B10KCNQ2ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 403 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119777031-A Polysaccharide-based thermoplastic composite fiber and preparation method thereof 中国科学院化学研究所 2025-04-08 CN claimed
CN-118496175-A TRADD inhibitor derivative and preparation method and application thereof 安徽医科大学 2024-08-16 CN claimed
CN-118255664-A Method for purifying phenylbutyrate 安徽沃泰生物医药有限公司 2024-06-28 CN claimed
CN-116193872-A Perovskite solar cell and passivation method thereof 北京航空航天大学 2023-05-30 CN claimed
CN-109980278-B Electrolyte and secondary lithium battery 张家港市国泰华荣化工新材料有限公司 2021-06-08 CN claimed
CN-107880189-B Catalyst component for olefin polymerization and preparation and application thereof 中国石油化工股份有限公司 2021-04-09 CN claimed
CN-107880194-B Catalyst component for olefin polymerization, preparation method thereof and catalyst 中国石油化工股份有限公司 2021-02-05 CN claimed
CN-107880172-B Catalyst component for olefin polymerization and preparation and application thereof 中国石油化工股份有限公司 2020-07-24 CN claimed
CN-107880169-B Catalyst component for olefin polymerization and preparation and application thereof 中国石油化工股份有限公司 2020-07-24 CN claimed
CN-107880195-B Catalyst component for olefin polymerization, preparation method thereof and catalyst 中国石油化工股份有限公司 2020-05-12 CN claimed
EP-2607388-B1 CATALYTIC COMPOSITION FOR POLYMERIZATION OF OLEFIN AND PREPARATION METHOD THEREOF CHINA PETROLEUM & CHEMICAL (CN) 2015-08-12 EP claimed
US-9068025-B2 Catalyst component for polymerization of olefin and preparation method CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2015-06-30 US claimed
EP-2607388-A1 CATALYTIC COMPOSITION FOR POLYMERIZATION OF OLEFIN AND PREPARATION METHOD THEREOF China Petroleum & Chemical Corporation (CN) 2013-06-26 EP claimed
US-20130150540-A1 CATALYST COMPONENT FOR POLYMERIZATION OF OLEFIN AND PREPARATION METHOD THEREOF BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2013-06-13 US claimed
EP-1506176-B1 AMINOINDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM PFIZER ITALIA SRL (IT) 2013-04-24 EP claimed
CN-102382054-A Parazole and isoxazole derivative, preparation method for same and application thereof UNIV PLA 2ND MILITARY MEDICAL 2012-03-21 CN claimed
US-20050154051-A1 Method for the preparation of escitalopram H. LUNDBECK A/S (DK) 2005-07-14 US claimed
CN-1602305-A Method for the preparation of escitalopram LUNDBECK & CO AS H (DK) 2005-03-30 CN claimed
EP-1458701-A1 METHOD FOR THE PREPARATION OF ESCITALOPRAM H. Lundbeck A/S (DK) 2004-09-22 EP claimed
WO-2003051861-A1 METHOD FOR THE PREPARATION OF ESCITALOPRAM H. LUNDBECK A/S (DK) 2003-06-26 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050154051-A1 Method for the preparation of escitalopram SLC6A4, TPH2, SLC6A3 LMNA 2498/4885HSD17B10 337/4885KCNQ2 778/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.