Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.31 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5828172 | 0.81 | FPR2 (0.39) | FPR2CYP1A2TDP1TP53KDM4E | |
| SCHEMBL5827619 | 0.81 | GNAI3 (0.35) | FPR2GNAI3GNAO1GNAI1CYP1A2 | |
| SCHEMBL5828038 | 0.80 | LMNA (0.37) | FPR2GNAI3GNAO1GNAI1CYP1A2 | |
| SCHEMBL22962395 | 0.70 | FPR2 (0.39) | FPR2GNAI3GNAO1GNAI1CYP1A2 | |
| SCHEMBL28748512 | 0.69 | NCF1 (0.39) | GNAI3GNAO1GNAI1TP53CACNA2D1 | |
| SCHEMBL5827842 | 0.69 | TP53 (0.35) | GNAI3GNAO1GNAI1TP53CHRM1 | |
| SCHEMBL5828493 | 0.69 | TP53 (0.35) | GNAI3GNAO1GNAI1TP53CHRM1 | |
| SCHEMBL10066711 | 0.68 | TP53 (0.50) | TP53POLB | |
| SCHEMBL5828173 | 0.68 | KDM4E (0.39) | FPR2CYP1A2TDP1TP53KDM4E | |
| SCHEMBL4921739 | 0.68 | NCF1 (0.37) | GNAI3GNAO1GNAI1TP53CACNA2D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7001904-B1 | Guanidine derivatives quinazoline and quinoline for use in the treatment of autoimmune diseases | ASTRAZENECA AB (SE) | 2006-02-21 | — | — | US | disclosed |