Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CYP4Z1 | Q86W10 | 9/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.49 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.49 |
| ▸ | CYP4F8 | P98187 | 1/20 | 0.49 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 3/20 | 0.45 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | SI | P14410 | 3/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5828526 | 0.83 | HCAR3 (0.50) | HPGD | |
| SCHEMBL238589 | 0.81 | CYP4Z1 (0.50) | APAF1POLBCYP4Z1CYP1A2CYP2C8 | |
| SCHEMBL5828225 | 0.80 | HCAR3 (0.60) | HPGD | |
| SCHEMBL9882895 | 0.79 | CYP4Z1 (0.50) | APAF1POLBCYP4Z1CYP1A2CYP2C8 | |
| SCHEMBL16335870 | 0.78 | CYP4Z1 (0.48) | APAF1POLBCYP4Z1CYP1A2CYP2C8 | |
| SCHEMBL5790948 | 0.73 | POLB (0.57) | APAF1POLBCYP1A2KMT2AKDM4E | |
| SCHEMBL5827487 | 0.72 | KDM4E (0.42) | APAF1POLBKMT2AKDM4ERAB9A | |
| SCHEMBL7173837 | 0.72 | KDM4E (0.42) | APAF1POLBKMT2AKDM4ERAB9A | |
| SCHEMBL1757405 | 0.71 | CYP4Z1 (0.50) | POLBCYP4Z1CYP1A2CYP2C8CYP2B6 | |
| SCHEMBL1757403 | 0.71 | CYP4Z1 (0.50) | POLBCYP4Z1CYP1A2CYP2C8CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050222426-A1 | Non-proteinogenic L-amino acids | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH | 2005-10-06 | — | — | US | claimed |
| US-20040197879-A1 | Process for producing non-proteinogenic L-amino acids by fermentation | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH | 2004-10-07 | — | — | US | claimed |
| US-20020039767-A1 | Process for producing non-proteinogenic L-amino acids by fermentation | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH | 2002-04-04 | — | — | US | claimed |
| EP-1191106-A1 | Verfahren zur fermentativen Herstellung von nicht-proteinogenen L-Aminosäuren | Consortium für elektrochemische Industrie GmbH (DE) | 2002-03-27 | — | — | EP | claimed |
| US-7015331-B2 | Non-proteinogenic L-amino acids | Consortium für elektrochemische Industrie GmbH (DE) | 2006-03-21 | — | — | US | disclosed |
| US-20050222426-A1 | Non-proteinogenic L-amino acids | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH | 2005-10-06 | — | — | US | disclosed |
| US-6939967-B2 | Non-proteinogenic L-amino acids | Consortium für elektrochemische Industrie GmbH (DE) | 2005-09-06 | — | — | US | disclosed |
| US-20040197879-A1 | Process for producing non-proteinogenic L-amino acids by fermentation | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH | 2004-10-07 | — | — | US | disclosed |
| US-6756216-B2 | BATCH PROCESSING USING NUCLEOPHILIC COMPOUND | Consortium für elektrochemische Industrie GmbH (DE) | 2004-06-29 | — | — | US | disclosed |
| EP-1191106-B1 | Process for the fermentative preparation of non-proteinogenic L-amino acids | CONSORTIUM ELEKTROCHEM IND (DE) | 2004-04-28 | — | — | EP | disclosed |
| US-20020039767-A1 | Process for producing non-proteinogenic L-amino acids by fermentation | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH | 2002-04-04 | — | — | US | disclosed |
| EP-1191106-A1 | Verfahren zur fermentativen Herstellung von nicht-proteinogenen L-Aminosäuren | Consortium für elektrochemische Industrie GmbH (DE) | 2002-03-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222426-A1 | Non-proteinogenic L-amino acids | BCAT2, BCAT1, CBS | APAF1 1306/4885POLB 2972/4885CYP4Z1 361/4885 |
| US-20020039767-A1 | Process for producing non-proteinogenic L-amino acids by fermentation | CBS, BCAT2, BCAT1 | APAF1 1011/4885POLB 2545/4885CYP4Z1 299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.