Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | RNF4 | P78317 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | MLNR | O43193 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5833116 | 0.85 | ROCK2 (0.41) | CHRM2CHRM3BCHE | |
| SCHEMBL5833542 | 0.85 | CHRM3 (0.44) | CHRM2CHRM3BCHE | |
| SCHEMBL5833026 | 0.82 | BCHE (0.41) | BCHE | |
| SCHEMBL5833447 | 0.82 | TACR1 (0.41) | BCHE | |
| SCHEMBL5833435 | 0.82 | SIGMAR1 (0.42) | CHRM2CHRM3BCHESIGMAR1 | |
| SCHEMBL5833940 | 0.82 | OPRD1 (0.43) | CHRM2CHRM3BCHE | |
| SCHEMBL5833270 | 0.80 | MLNR (0.40) | CHRM2CHRM3BCHEMLNR | |
| SCHEMBL5844908 | 0.79 | LMNA (0.36) | CHRM2CHRM3BCHE | |
| SCHEMBL5833278 | 0.78 | RNF4 (0.42) | CHRM2CHRM3RNF4PAX8LTA4H | |
| SCHEMBL5833006 | 0.78 | HTT (0.38) | BCHESIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7008955-B2 | (2-azabicyclo[2.2.1]hept-7yl) methanol derivatives as nicotinic acetylcholine receptor agonists | MERCK PATENT GMBH (DE) | 2006-03-07 | — | — | US | claimed |