Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 4/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5833270 | 0.85 | MLNR (0.40) | BCHECHRM2CHRM3CHRM1 | |
| SCHEMBL5833542 | 0.85 | CHRM3 (0.44) | OPRM1OPRK1BRD4BCHECHRM2 | |
| SCHEMBL5833116 | 0.83 | ROCK2 (0.41) | KMT2ABRD4HTTBCHECHRM2 | |
| SCHEMBL5833281 | 0.82 | CHRM2 (0.40) | BCHECHRM2CHRM3 | |
| SCHEMBL5833026 | 0.81 | BCHE (0.41) | KMT2ABRD4HTTBCHE | |
| SCHEMBL5833435 | 0.81 | SIGMAR1 (0.42) | L3MBTL1KMT2ABCHECHRM2CHRM3 | |
| SCHEMBL5833447 | 0.81 | TACR1 (0.41) | KMT2ABCHE | |
| SCHEMBL5833937 | 0.79 | OPRD1 (0.47) | OPRD1OPRM1OPRK1L3MBTL1KMT2A | |
| SCHEMBL5844908 | 0.79 | LMNA (0.36) | L3MBTL1KMT2AHTTBCHEALDH1A1 | |
| SCHEMBL5833006 | 0.76 | HTT (0.38) | L3MBTL1BRD4HTTBCHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7008955-B2 | (2-azabicyclo[2.2.1]hept-7yl) methanol derivatives as nicotinic acetylcholine receptor agonists | MERCK PATENT GMBH (DE) | 2006-03-07 | — | — | US | claimed |