Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5844908 | 0.84 | LMNA (0.36) | HTTALDH1A1MAPTSMN1; SMN2BCHE | |
| SCHEMBL5833026 | 0.79 | BCHE (0.41) | HTTSMN1; SMN2BCHEBRD4 | |
| SCHEMBL5833003 | 0.79 | SIGMAR1 (0.41) | HTTALDH1A1LMNASIGMAR1AR | |
| SCHEMBL5833281 | 0.78 | CHRM2 (0.40) | BCHESIGMAR1 | |
| SCHEMBL5833542 | 0.77 | CHRM3 (0.44) | BCHEBRD4 | |
| SCHEMBL5833116 | 0.77 | ROCK2 (0.41) | HTTSMN1; SMN2BCHEBRD4 | |
| SCHEMBL5833940 | 0.76 | OPRD1 (0.43) | HTTALDH1A1BCHEBRD4L3MBTL1 | |
| SCHEMBL5833435 | 0.76 | SIGMAR1 (0.42) | BCHESIGMAR1MAPK1L3MBTL1 | |
| SCHEMBL5833447 | 0.76 | TACR1 (0.41) | BCHE | |
| SCHEMBL5833270 | 0.74 | MLNR (0.40) | BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7008955-B2 | (2-azabicyclo[2.2.1]hept-7yl) methanol derivatives as nicotinic acetylcholine receptor agonists | MERCK PATENT GMBH (DE) | 2006-03-07 | — | — | US | claimed |