Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOD1 | P00441 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | QPCT | Q16769 | 8/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5842900 | 0.99 | SOD1 (0.46) | SOD1LMNAMAPTQPCTNPC1 | |
| SCHEMBL2539814 | 0.86 | SOD1 (0.57) | SOD1QPCTNPC1RAB9AATM | |
| Hydrochloric Acid SCHEMBL5191266 | 0.84 | SOD1 (0.56) | SOD1QPCTNPC1RAB9AATM | |
| SCHEMBL5837274 | 0.83 | MAOA (0.58) | SOD1MAPTQPCTNPC1RAB9A | |
| SCHEMBL5903394 | 0.74 | NPC1 (0.55) | SOD1MAPTQPCTNPC1RAB9A | |
| SCHEMBL11495035 | 0.73 | SOD1 (0.67) | SOD1QPCTNPC1RAB9AATM | |
| SCHEMBL27418532 | 0.72 | HMOX1 (0.61) | SOD1LMNAQPCTNPC1RAB9A | |
| SCHEMBL5754898 | 0.71 | NPC1 (0.47) | SOD1LMNAMAPTQPCTNPC1 | |
| SCHEMBL24349153 | 0.71 | TOP1 (0.43) | SOD1LMNAMAPTQPCTNPC1 | |
| SCHEMBL291484 | 0.71 | QPCT (0.54) | SOD1LMNAQPCTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7132534-B2 | Para-phenylenediamine derivatives containing a pyrrolidyl group, and use of these derivatives for coloring keratin fibers | L'OREAL (FR) | 2006-11-07 | — | — | US | claimed |
| US-20040077852-A1 | Para-phenylenediamine derivatives containing a pyrrolidyl group, and use of these derivatives for coloring keratin fibers | L'OREAL S.A. (FR) | 2004-04-22 | — | — | US | claimed |
| US-7132534-B2 | Para-phenylenediamine derivatives containing a pyrrolidyl group, and use of these derivatives for coloring keratin fibers | L'OREAL (FR) | 2006-11-07 | — | — | US | disclosed |
| US-20040077852-A1 | Para-phenylenediamine derivatives containing a pyrrolidyl group, and use of these derivatives for coloring keratin fibers | L'OREAL S.A. (FR) | 2004-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077852-A1 | Para-phenylenediamine derivatives containing a pyrrolidyl group, and use of these derivatives for coloring keratin fibers | KRT18, CDC73, VIM | SOD1 3425/4885LMNA 451/4885MAPT 1211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.