Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 4/20 | 0.32 |
| ▸ | HTR7 | P34969 | 4/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6056122 | 0.93 | PDCD1 (0.30) | PDCD1CD274 | |
| SCHEMBL29366427 | 0.84 | PDCD1 (0.34) | GPR55ADRA2AADRA2BADRA2CCHRNB2 | |
| SCHEMBL61908 | 0.84 | PDCD1 (0.34) | GPR55ADRA2AADRA2BADRA2CCHRNB2 | |
| SCHEMBL2707582 | 0.83 | PTGS1 (0.37) | MAPTKDM4EALDH1A1TP53HPGD | |
| SCHEMBL1453397 | 0.83 | RAB9A (0.37) | MAPTKDM4EALDH1A1TP53NFKB1 | |
| Hydrochloric Acid SCHEMBL3822639 | 0.81 | ADRA2A (0.34) | ADRA2AADRA2BADRA2CCHRNB2CHRNA4 | |
| Dimethylamine SCHEMBL1453283 | 0.80 | TDO2 (0.33) | ADRA2AADRA2BADRA2CCHRNB2CHRNA4 | |
| SCHEMBL5836913 | 0.80 | ADRB2 (0.33) | ADRA2AADRA2BADRA2CCHRNB2CHRNA4 | |
| SCHEMBL5837020 | 0.80 | ADRA2A (0.32) | ADRA2AADRA2BADRA2CCHRNB2CHRNA4 | |
| SCHEMBL6056086 | 0.79 | PTGS2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6984743-B1 | Method for producing metallocenes | BASELL POLYOLEFINE GMBH (DE) | 2006-01-10 | — | — | US | disclosed |
| EP-1015463-B1 | METHOD FOR PRODUCING METALLOCENES | BASELL POLYOLEFINE GMBH (DE) | 2002-12-11 | — | — | EP | disclosed |