Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 6/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 13/20 | 0.33 |
| ▸ | CNR1 | P21554 | 6/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5838696 | 0.76 | CXCR2 (0.42) | CXCR2 | |
| SCHEMBL5838665 | 0.75 | ADORA1 (0.33) | P2RX3 | |
| SCHEMBL29814606 | 0.73 | TAS1R3 (0.40) | P2RX3 | |
| SCHEMBL31303339 | 0.73 | TAS1R3 (0.40) | P2RX3 | |
| SCHEMBL5837829 | 0.72 | CXCR2 (0.36) | CXCR2 | |
| SCHEMBL7471265 | 0.67 | ACHE (0.31) | — | |
| SCHEMBL6315716 | 0.64 | CXCR2 (0.54) | CXCR2CNR2 | |
| SCHEMBL5838657 | 0.62 | ALDH1A1 (0.37) | — | |
| SCHEMBL10086371 | 0.62 | TP53 (0.44) | — | |
| SCHEMBL5837610 | 0.61 | MAPT (0.33) | CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7115624-B1 | Method of inhibiting protein tyrosine phosphatase 1B and/or T-cell protein tyrosine phosphatase 4 and/or other PTPases with an Asp residue at position 48 | NOVO NORDISK A/S (DK) | 2006-10-03 | — | — | US | disclosed |