Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474476 | 0.86 | PDE4D (0.32) | BRD4CREBBPPOLB | |
| SCHEMBL7464864 | 0.83 | KDM4E (0.34) | BRD4CREBBPSMN1; SMN2 | |
| SCHEMBL7473472 | 0.83 | GABRA1 (0.35) | — | |
| SCHEMBL29814606 | 0.73 | TAS1R3 (0.40) | ACHEHPGDMEN1KMT2A | |
| SCHEMBL31303339 | 0.73 | TAS1R3 (0.40) | ACHEHPGDMEN1KMT2A | |
| SCHEMBL7563099 | 0.72 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL5838665 | 0.69 | ADORA1 (0.33) | — | |
| SCHEMBL7479571 | 0.67 | STING1 (0.30) | — | |
| SCHEMBL5838706 | 0.67 | CXCR2 (0.42) | — | |
| SCHEMBL7476167 | 0.64 | ALDH1A1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214325-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPases) | NOVO NORDISK A/S (DK) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001019831-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPases) | NOVO NORDISK A/S (DK) | 2001-03-22 | — | — | WO | disclosed |