Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.34 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.34 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 3/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL583885 | 0.70 | PTGS2 (0.38) | TXNRD1TXNRD3TXNRD2AOC3ABCG2 | |
| SCHEMBL2886044 | 0.64 | MAPT (0.42) | TXNRD1TXNRD3TXNRD2ALDH1A1HSD17B10 | |
| SCHEMBL25166052 | 0.63 | NQO2 (0.44) | TXNRD1TXNRD3TXNRD2AOC3ABCG2 | |
| SCHEMBL8334782 | 0.61 | NQO2 (0.46) | TXNRD1TXNRD3TXNRD2AOC3ABCG2 | |
| SCHEMBL20861806 | 0.61 | CA1 (0.38) | TXNRD1TXNRD3TXNRD2AOC3CYP3A4 | |
| SCHEMBL14302835 | 0.60 | CYP1A2 (0.51) | ABCG2PTGS2KDM4ETSHRCYP1A2 | |
| SCHEMBL10430779 | 0.60 | POLB (0.43) | CYP2D6NQO2CYP19A1CYP1A2 | |
| SCHEMBL7271090 | 0.60 | NQO2 (0.38) | TXNRD1TXNRD3TXNRD2XBP1AOC3 | |
| SCHEMBL7594061 | 0.60 | ABCG2 (0.55) | TXNRD1TXNRD3TXNRD2ABCG2PTGS2 | |
| SCHEMBL9488966 | 0.59 | ALOX5 (0.47) | TXNRD1TXNRD3TXNRD2PTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077989-A1 | CYCLIC IMIDATE LIGANDS | UNIVERSITEIT GENT (BE) | 2012-03-29 | — | — | US | disclosed |
| EP-2416879-A1 | CYCLIC IMIDATE LIGANDS | Universiteit Gent (BE) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010115903-A1 | CYCLIC IMIDATE LIGANDS | UNIVERSITEIT GENT (BE) | 2010-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077989-A1 | CYCLIC IMIDATE LIGANDS | IDH2, CYCS, NAPRT | TXNRD1 4473/4885TXNRD3 4131/4885TXNRD2 3923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.