Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PRNP | P04156 | 1/20 | 0.31 |
| ▸ | LCLAT1 | Q6UWP7 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21218733 | 0.84 | CES2 (0.41) | CES2BCHECES1ALDH1A1 | |
| SCHEMBL8896144 | 0.79 | NPC1 (0.38) | LMNAALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL11135091 | 0.78 | CES2 (0.43) | CTSLCES2BCHECES1MAOB | |
| SCHEMBL22540 | 0.77 | CES2 (0.58) | CTSLCES2BCHECES1ALDH1A1 | |
| SCHEMBL16960814 | 0.76 | CTSL (0.38) | CTSLCES2BCHECES1MAOB | |
| SCHEMBL9217406 | 0.74 | CES2 (0.43) | CTSLCES2BCHECES1MAOB | |
| SCHEMBL11883495 | 0.74 | KAT6A (0.41) | CES2BCHECES1ALDH1A1GAA | |
| SCHEMBL29570698 | 0.74 | PRNP (0.50) | CES2BCHECES1ALDH1A1PRNP | |
| SCHEMBL146386 | 0.74 | PRNP (0.50) | CES2BCHECES1ALDH1A1PRNP | |
| SCHEMBL362461 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6984747-B2 | Method for preparing styryl-functionalized silanes | FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) | 2006-01-10 | — | — | US | disclosed |
| EP-1318153-B1 | Process for the preparation of styrylsilanes | FRAUNHOFER GES FORSCHUNG (DE) | 2004-08-04 | — | — | EP | disclosed |
| US-20030139621-A1 | Method for preparing styryl-functionalized silanes | FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V. | 2003-07-24 | — | — | US | disclosed |
| EP-1318153-A1 | Process for the preparation of styrylsilanes | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2003-06-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139621-A1 | Method for preparing styryl-functionalized silanes | SPTSSB, SIRT5, EIF2B2 | CTSL 4597/4885CES2 3657/4885BCHE 4484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.