SCHEMBL5839563

SCHEMBL5839563

c1ccc(C(c2ccccc2-n2cnnn2)(c2ccccc2-n2cnnn2)c2ccccc2-n2cnnn2)c(-n2cnnn2)c1

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 6/20 0.56
▸ NPSR1 Q6W5P4 1/20 0.56
▸ NOTUM Q6P988 5/20 0.52
▸ KMT2A Q03164 3/20 0.44
▸ KDM4E B2RXH2 1/20 0.44
▸ NPC1 O15118 1/20 0.41
▸ F2 P00734 1/20 0.40
▸ MAPT P10636 1/20 0.40
▸ TSHR P16473 1/20 0.39
▸ HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4324877 0.85 ALDH1A1 (0.53) ALDH1A1NPSR1NOTUMKMT2AKDM4E
SCHEMBL12615992 0.83 ALDH1A1 (0.68) ALDH1A1NPSR1NOTUMKMT2AKDM4E
SCHEMBL5549180 0.74 ALDH1A1 (0.58) ALDH1A1NPSR1NOTUMKMT2AKDM4E
SCHEMBL436604 0.74 ALDH1A1 (0.58) ALDH1A1NPSR1NOTUMKMT2AKDM4E
SCHEMBL30084182 0.74 ALDH1A1 (0.58) ALDH1A1NPSR1NOTUMKMT2AKDM4E
SCHEMBL8109135 0.74 ALDH1A1 (0.58) ALDH1A1NPSR1NOTUMKMT2AKDM4E
SCHEMBL5330184 0.74 ALDH1A1 (0.58) ALDH1A1NPSR1NOTUMKMT2AKDM4E
SCHEMBL14242848 0.74 ALDH1A1 (0.58) ALDH1A1NPSR1NOTUMKMT2AKDM4E
SCHEMBL8540440 0.74 ALDH1A1 (0.58) ALDH1A1NPSR1NOTUMKMT2AKDM4E
SCHEMBL28955008 0.74 ALDH1A1 (0.58) ALDH1A1NPSR1NOTUMKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12629639-B2 Spacer for a spiral wound membrane EVOVE LTD (GB) 2026-05-19 — — US disclosed
EP-4397399-A2 MEMBRANES COMPRISING A LAYER OF METAL ORGANIC FRAMEWORK PARTICLES G2O Water Technologies Limited (GB) 2024-07-10 — — EP disclosed
US-20240157304-A1 SPACER FOR A SPIRAL WOUND MEMBRANE EVOVE LTD (GB) 2024-05-16 — — US disclosed
US-20240149223-A1 MEMBRANE DEVICE EVOVE LTD (GB) 2024-05-09 — — US disclosed
EP-4304765-A1 SPACER FOR A SPIRAL WOUND MEMBRANE Evove Ltd (GB) 2024-01-17 — — EP disclosed
EP-4304766-A1 MEMBRANE DEVICE Evove Ltd (GB) 2024-01-17 — — EP disclosed
WO-2022189793-A1 MEMBRANE DEVICE EVOVE LTD (GB) 2022-09-15 — — WO disclosed
WO-2022189785-A1 SPACER FOR A SPIRAL WOUND MEMBRANE EVOVE LTD (GB) 2022-09-15 — — WO disclosed
EP-3774001-A1 MEMBRANES COMPRISING A LAYER OF METAL ORGANIC FRAMEWORK PARTICLES G2O Water Technologies Limited (GB) 2021-02-17 — — EP disclosed
US-20210016232-A1 MEMBRANES COMPRISING A LAYER OF METAL ORGANIC FRAMEWORK PARTICLES EVOVE LTD (GB) 2021-01-21 — — US disclosed
US-9190114-B1 Disk drive filter including fluorinated and non-fluorinated nanopourous organic framework materials WESTERN DIGITAL TECHNOLOGIES, INC. (US) 2015-11-17 — — US disclosed
US-7052783-B2 Oxadiazole tetramers ACADEMIA SINICA (TW) 2006-05-30 — — US disclosed
US-20020102433-A1 Oxadizaole tetramers ACADEMIA SINICA (TW) 2002-08-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12629639-B2 Spacer for a spiral wound membrane AQP1, AQP3, AQP4 ALDH1A1 1090/4885NPSR1 3455/4885NOTUM 4378/4885
US-20020102433-A1 Oxadizaole tetramers NR4A1, NR0B1, NR0B2 ALDH1A1 1330/4885NPSR1 282/4885NOTUM 1867/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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