SCHEMBL584232

SCHEMBL584232

Oc1cc2c(c3ccccc13)C(CCl)CN2

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ADH1A P07327 2/20 0.45
KIT P10721 2/20 0.45
FLT1 P17948 2/20 0.45
KDR P35968 2/20 0.45
ABL2 P42684 2/20 0.45
FLT4 P35916 1/20 0.45
TRPM4 Q8TD43 1/20 0.33
F2 P00734 1/20 0.32
F10 P00742 1/20 0.32
PRSS1 P07477 1/20 0.32
LMNA P02545 1/20 0.32
HTT P42858 1/20 0.32
IDO1 P14902 1/20 0.31
CSNK2A2 P19784 1/20 0.30
CSNK2B P67870 1/20 0.30
CSNK2A1 P68400 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29375160 1.00 ADH1A (0.45) ADH1AKITFLT1KDRABL2
SCHEMBL31413354 1.00 ADH1A (0.45) ADH1AKITFLT1KDRABL2
SCHEMBL13293994 1.00 ADH1A (0.45) ADH1AKITFLT1KDRABL2
SCHEMBL31413355 1.00 ADH1A (0.45) ADH1AKITFLT1KDRABL2
SCHEMBL9885494 1.00 ADH1A (0.45) ADH1AKITFLT1KDRABL2
Hydrochloric Acid SCHEMBL30944523 0.98 ADH1A (0.44) ADH1AKITFLT1KDRABL2
Hydrochloric Acid SCHEMBL16933151 0.98 ADH1A (0.44) ADH1AKITFLT1KDRABL2
SCHEMBL13564476 0.85 ADH1A (0.34) ADH1AKITFLT1KDRABL2
SCHEMBL13564469 0.85 ADH1A (0.34) ADH1AKITFLT1KDRABL2
SCHEMBL14527500 0.85 ADH1A (0.34) ADH1AKITFLT1KDRABL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109789158-B RUNX inhibitors 国立大学法人京都大学 2022-06-03 CN claimed
US-11235001-B2 RUNX inhibitor KYOTO UNIVERSITY (JP) 2022-02-01 US claimed
US-20190247425-A1 RUNX INHIBITOR KYOTO UNIVERSITY (JP) 2019-08-15 US claimed
EP-3492087-A1 RUNX INHIBITOR Kyoto University (JP) 2019-06-05 EP claimed
WO-2015038426-A1 SELF-IMMOLATIVE LINKERS CONTAINING MANDELIC ACID DERIVATIVES, DRUG-LIGAND CONJUGATES FOR TARGETED THERAPIES AND USES THEREOF ASANA BIOSCIENCES, LLC (US) 2015-03-19 WO claimed
EP-2044436-B1 METHODS AND COMPOSITIONS FOR DETECTION OF MICROORGANISMS AND CELLS AND TREATMENT OF DISEASES AND DISORDERS GENELUX CORP (US) 2014-06-04 EP claimed
EP-2028270-B9 Modified recombinant vaccinia viruses, uses thereof GENELUX CORP (US) 2012-04-25 EP claimed
EP-2028270-B1 Modified recombinant vaccinia viruses, uses thereof GENELUX CORP (US) 2012-02-15 EP claimed
EP-1644492-B1 MODIFIED RECOMBINANT VACCINIA VIRUSES, USES THEREOF GENELUX CORP (US) 2009-01-07 EP claimed
US-20260137773-A1 ONCOLYTIC VACCINIA VIRUSES AND RECOMBINANT VIRUSES AND METHODS OF USE THEREOF VIROMISSILE, INC. (US) 2026-05-21 US disclosed
US-20260102417-A1 COMPOSITIONS FOR THE TREATMENT AND PREVENTION OF CANCER KEYZELL HOLDING S L (ES) 2026-04-16 US disclosed
EP-4208564-B1 NUCLEIC ACID MODIFYING REAGENTS AND USES THEREOF PROMEGA CORP (US) 2026-04-08 EP disclosed
US-12571031-B2 Nucleic acid modifying reagents and uses thereof PROMEGA CORPORATION (US) 2026-03-10 US disclosed
US-20260027226-A1 ANTIBODY-DRUG CONJUGATES PHEON THERAPEUTICS LTD (GB) 2026-01-29 US disclosed
WO-2007038658-A2 ANTIBODY-DRUG CONJUGATES AND METHODS OF USE MEDAREX, INC. (US) 2007-04-05 WO disclosed
EP-1731519-A1 NOVEL INDOLE DERIVATIVE FOR ALKYLATING SPECIFIC BASE SEQUENCE OF DNA AND ALKYLATING AGENT AND DRUG EACH COMPRISING THE SAME TMRC Co., Ltd. (JP) 2006-12-13 EP disclosed
EP-1644492-A2 MODIFIED RECOMBINANT VACCINIA VIRUSES AND OTHER MICROORGANISMS, USES THEREOF Genelux Corporation (US) 2006-04-12 EP disclosed
EP-1320522-B1 COMPOSITIONS AND METHODS OF THE USE THEREOF ACHIRAL ANALOGUES OF CC-1065 AND THE DUOCARMYCINS TAIHO PHARMACEUTICAL CO LTD (JP) 2005-11-23 EP disclosed
WO-2005047458-A2 MODIFIED RECOMBINANT VACCINA VIRUSES AND OTHER MICROORGANISMS, USES THEREOF GENELUX CORPORATION (US) 2005-05-26 WO disclosed
US-6559125-B1 Alkylator linked to a polyamide, wherein polyamide comprises at least one pyrrole or imidazole amino acid and wherein polyamide comprises a gamma-aminobutyric acid linked to alkylator; alkylator selectively alkylates one strand of DNA CALIFORNIA INSTITUTE OF TECHNOLOGY 2003-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260102417-A1 COMPOSITIONS FOR THE TREATMENT AND PREVENTION OF CANCER TACR1, TACR2, NPSR1 ADH1A 1497/4885KIT 34/4885FLT1 929/4885
US-20260137773-A1 ONCOLYTIC VACCINIA VIRUSES AND RECOMBINANT VIRUSES AND METHODS OF USE THEREOF CASP9, TP53, CASP2 ADH1A 4556/4885KIT 4229/4885FLT1 840/4885
US-20190247425-A1 RUNX INHIBITOR RUNX1, MLX, CBX2 ADH1A 3636/4885KIT 34/4885FLT1 2171/4885
US-11235001-B2 RUNX inhibitor RUNX1, MLX, CBX2 ADH1A 3636/4885KIT 34/4885FLT1 2171/4885
US-20260027226-A1 ANTIBODY-DRUG CONJUGATES SLC3A2, MTCL3, SLC13A2 ADH1A 1023/4885KIT 3669/4885FLT1 281/4885
US-12571031-B2 Nucleic acid modifying reagents and uses thereof POLRMT, ADAR, NCL ADH1A 2607/4885KIT 2505/4885FLT1 3821/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.