Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LYPLA1 | O75608 | 4/20 | 0.55 |
| ▸ | LYPLA2 | O95372 | 4/20 | 0.55 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.55 |
| ▸ | PLA2G6 | O60733 | 2/20 | 0.55 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.55 |
| ▸ | PNLIP | P16233 | 4/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | DAGLA | Q9Y4D2 | 4/20 | 0.46 |
| ▸ | PRKCA | P17252 | 3/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | PRKCG | P05129 | 1/20 | 0.44 |
| ▸ | PRKCB | P05771 | 1/20 | 0.44 |
| ▸ | PRKCH | P24723 | 1/20 | 0.44 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.44 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1840959 | 0.82 | THRB (0.66) | THRBTHRA | |
| SCHEMBL1837008 | 0.82 | THRB (0.66) | THRBTHRA | |
| SCHEMBL1838051 | 0.82 | THRB (0.66) | THRBTHRA | |
| SCHEMBL1951721 | 0.82 | THRB (0.66) | THRBTHRA | |
| SCHEMBL1835737 | 0.82 | THRB (0.66) | THRBTHRA | |
| SCHEMBL1839479 | 0.82 | THRB (0.66) | THRBTHRA | |
| SCHEMBL5847250 | 0.81 | LYPLA1 (0.51) | LYPLA1LYPLA2ABHD16APLA2G6PLA2G4A | |
| SCHEMBL1838228 | 0.80 | THRB (0.67) | THRBTHRA | |
| SCHEMBL19514898 | 0.80 | PLA2G6 (0.84) | LYPLA1LYPLA2ABHD16APLA2G6PLA2G4A | |
| SCHEMBL19514903 | 0.80 | PLA2G6 (0.84) | LYPLA1LYPLA2ABHD16APLA2G6PLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074822-B2 | Alkyl carbamate-substituted β-lactones, process for their preparation, and pharmaceutical compositions containing them | SOLVAY PHARMACEUTICALS GMBH (DE) | 2006-07-11 | — | — | US | disclosed |
| US-20050197386-A1 | Alkyl carbamate-substituted beta-lactones, process and intermediate products for their preparation, and pharmaceutical compositions containing them | SOLVAY PHARMACEUTICALS GMBH (DE) | 2005-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050197386-A1 | Alkyl carbamate-substituted beta-lactones, process and intermediate products for their preparation, and pharmaceutical compositions containing them | PNLIP, CEL, LIPE | LYPLA1 19/4885LYPLA2 28/4885ABHD16A 38/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.